I started studying Hashimoto’s in 2009, right after my own diagnosis. The protocols I’ve developed over the years and shared in my books, will help about 80 percent of people feel significantly better. However, I’m always on the lookout for new protocols and the latest research to help more people heal. I was really excited that a new study has shown that aloe vera can be beneficial for Hashimoto’s – it has been found to reduce thyroid antibodies, as well as improve TSH and free T4 levels.
In the past, I had occasionally used aloe vera to support gut health with great results, but didn’t realize just how impactful it could be for antibodies and thyroid markers, until recently.
Aloe vera has numerous benefits, both when taken orally and applied topically, and has been an essential healing plant in many cultures, for thousands of years. Traditionally, the plant has been used as a great household remedy to treat wounds, soothe itching, and help reduce tissue scarring.
It has also been used for a variety of conditions, including constipation, blood sugar issues, infections, and inflammation.
Since such conditions are often co-occurring in people with autoimmune thyroid disease, aloe vera can be used to help reverse them. I am so excited to share with you just how this plant can benefit those with Hashimoto’s!
In this article, you’ll learn about:
- How aloe vera can help the thyroid
- How aloe vera can support gut and immune health
- How aloe vera may be beneficial for stress levels
- Specific aloe vera supplement recommendations and important precautions
What is Aloe Vera?
Aloe vera (Aloe barbadensis) is one of the oldest mentioned plants known for its medicinal properties. Originating from the Arabian peninsula, this succulent (a member of the lily family) was first recorded to be used by the ancient Egyptians as a treatment for wounds and burns.
Cleopatra was even known to use aloe during her skincare sessions, likely because aloe vera gel (the clear jelly-like substance found in aloe leaves) is almost 99 percent water and can be very hydrating to the skin. In fact, it can be used topically to help reduce fine lines and wrinkles.
Aloe vera is now cultivated in many countries throughout the world.
Today, it is favored as a great houseplant. I often recommend that people keep multiple aloe vera plants in their homes or offices. Aloe is easy to care for and requires minimal sunlight.
Aside from being a practical plant, aloe vera has been touted as a nutritional powerhouse, as it is packed full of antioxidants and anti-inflammatory components. The leaf of aloe contains vitamins C, E, and A, as well as many essential B vitamins: B12, niacin, B6, folate, and biotin. Aloe vera is unique in that it is rich in vitamin B12, which very few plants are. (Typically, this energy-supporting B vitamin is only found in animal products such as fish, meat, eggs, and milk.)
Aloe vera also contains minerals and trace minerals which are vital for thyroid protection and a healthy conversion from T4 to T3 – these include chromium, zinc, selenium, copper, magnesium, sodium, potassium, and calcium. (One reason why I love aloe vera so much is because its nutritional profile can help address some nutrient deficiencies associated with Hashimoto’s!)
Another unique feature of aloe vera is that it contains many amino acids, which are essential for the body (meaning our body cannot produce them on its own). One amino acid in aloe vera that I find particularly interesting is tyrosine, which is the precursor amino acid for thyroxine, also known as… thyroid hormone. 🙂
Aloe Vera for Thyroid Health
As I mentioned previously, aloe vera can benefit those with Hashimoto’s and thyroid conditions, in multiple ways.
I was really excited to learn about a new study from Italy, which focused specifically on the benefits of aloe vera in Hashimoto’s. Interestingly, one of the researchers who initiated the study saw that her own Hashimoto’s markers improved after she began drinking aloe vera on a daily basis, to soothe her digestion and use as a laxative for constipation.
The researcher had routine lab work done to track her Hashimoto’s markers every few months.
Prior to starting daily aloe vera, her TSH was 5.14 μIU/mL, her free T4 was 8.3 pmol/L, and her TPO antibodies were 1875 IU/mL.
Three months after the start of her aloe vera regimen, her TSH dropped to 3.22 μIU/mL, her free T4 improved to 11.44 pmol/L, and her thyroid antibodies dropped to 778 IU/mL.
Another six months later, her labs continued to improve even further: her TSH was within optimal range at 1.83 μIU/mL, and her thyroid antibodies dropped again to 24 IU/mL, which is considered “negative” for Hashimoto’s, according to most labs! I love that Root Cause Rebels are everywhere, and that this particular rebel decided to help the Hashimoto’s community through published research based on her own experience — a woman after my own heart. 🙂
The study used 50 mL of Aloe barbadensis miller juice (or ABMJ, which is the botanical name for the aloe vera plant) twice daily, for a period of nine months, in 30 women with Hashimoto’s thyroiditis and subclinical hypothyroidism. (An additional 15 women served as controls.)
After the nine-month trial, there was a decrease in serum TSH and TPO antibodies (a 54 percent reduction!), as well as an increase in serum free T4, in those who took aloe vera daily. Interestingly, serum free T3 declined by 16 percent after 3 months, with no further decline after another six months.
Interestingly, aloe vera was as effective as selenium, one of the well-known and often recommended nutrients for Hashimoto’s. In general, selenium (Selenomethionine at 200 IU a day, for six months), has been shown to reduce TPO antibodies by up to 54 percent and is one of my key go-to initial recommendations for Hashimoto’s.
With respect to selenium, I often see that in terms of symptoms, people will see a reduction in anxiety and hair loss. This particular study didn’t report the symptom benefits that aloe provided, but in clients who have used it, mostly gut-related symptoms (like constipation and stomach discomfort) improved. Nonetheless, based on the success of this recent study, I do believe aloe vera may be beneficial for those with Hashimoto’s, and I will be looking out for more research being published on this topic.
The Benefits of Aloe Vera
Aloe vera can decrease thyroid antibody levels, positively affect our thyroid hormone levels, and be beneficial for other conditions which may co-occur with Hashimoto’s, including:
- Food sensitivities
- Nutrient depletions
- An impaired ability to handle stress (including blood sugar imbalances)
- An impaired ability to handle toxins
- Gut issues
- Infections
I often say that Hashimoto’s is a combination of the above, and that’s not even an exhaustive list!
Let’s explore how aloe vera can help.
Gut Health and Digestion
Aloe vera has been known to balance the digestive system, as well as reduce inflammation within the colon and small intestine. This is an incredibly helpful mechanism, as intestinal permeability (also known as leaky gut) is one of the three factors that must be present for an autoimmune condition to occur.
In other words, most people with Hashimoto’s will present with gut issues – and many of us with autoimmune thyroiditis may be able to reverse symptoms and the condition itself, by healing intestinal inflammation and improving our gut health.
One way that aloe vera can help address gut health is by improving one’s digestion. Aloe vera is full of enzymes (alliinase, alkaline phosphatase, amylase, bradykinase, carboxypeptidase, catalase, cellulase, lipase, and peroxidase). Since many people with Hashimoto’s are deficient in digestive enzymes, aloe vera’s high enzyme content can actually support digestion by breaking down carbohydrates and fats from foods.
Containing 75 active constituents, aloe vera is also abundant in saccharides (sugars). These sugars are an excellent source of fiber and prebiotics (a form of dietary fiber that acts as a fertilizer for probiotics – AKA good gut bacteria), which support the digestive tract in absorbing toxins and excess hormones.
Interestingly, a study completed in 2012 showed the effects of aloe vera juice on the growth of the probiotic Lactobacilli. The results showed an improvement in the growth of the different Lactobacilli such as L. acidophilus, L. plantarum, and L. casei in the lab. This is helpful because increasing the amount of beneficial bacteria in one’s gut can put gut-related symptoms into remission!
I particularly like anything that helps with the growth of L. casei, as this probiotic can help with breaking down casein, a common reactive protein present in dairy that many with Hashimoto’s and autoimmune conditions may find triggering.
Aloe vera also can help with acid reflux, which is a common symptom of Hashimoto’s and hypothyroidism. Aloe vera contains natural alkaline properties which can help balance the pH in the colon. Though many people with Hashimoto’s have a lack of stomach acid that will cause symptoms of acid reflux, those who have an overabundance of stomach acid and are at risk for ulcers, may benefit from the alkalizing properties of aloe. Studies have shown aloe vera to be well tolerated and as effective in reducing symptoms of gastroesophageal reflux disease as common reflux medications (such as omeprazole or ranitidine).
Lastly, aloe vera has been shown to improve irritable bowel disease (IBD) and ulcerative colitis (UC). Aloe vera has potent anti-inflammatory and antioxidant properties that help reduce inflammation and oxidative damage, as well as help balance the immune system, in those with IBD and UC. In a 2020 study, researchers induced UC in rats to investigate the benefits of aloe vera as a treatment option. They found that aloe vera significantly reduced pathological processes seen in UC, such as bleeding of intestinal mucus, thickening of intestinal mucus, as well as ulcers and tissue damage in the intestines.
Liver Health – Impaired Ability to Handle Toxins
Aloe vera has been shown to protect the liver from oxidative stress-induced damage (that is, damage caused by an imbalance between the production of harmful free radicals, and the body’s ability to counteract them with antioxidants) in animal studies. This may be due to the plant’s high amino acid content. A 2013 animal study that used aloe vera gel daily, for a period of 21 days, found that aloe vera gel helped with normalizing elevated liver enzymes (a marker of liver disease), with markers returning to the normal or near-normal range for most.
I have previously discussed how a liver “backlog” can lead to poor detoxification and multiple symptoms, as well as impair the conversion of the T4 thyroid hormone to the biologically active T3 hormone.
Stress and Adrenal Support
Aloe vera is an adaptogen, which is a substance that can increase the body’s resilience to different types of stress, including physical and emotional stress. Often, ongoing stress, or even an acutely stressful situation, opens the door to autoimmune disorders. Many of my clients have noticed that their thyroid symptoms began after experiencing a particularly stressful period in their life.
An existing or recent diagnosis of Hashimoto’s can further the stress response, leading to a decrease in sleep quality, blood sugar imbalances, and added emotional stress – all of which are factors that can wreak havoc on our adrenals, which help us respond to stress, yet often take the biggest hit when we are overwhelmed. To fully heal, we must turn down our stress response (also known as our fight-or-flight response).
For this reason, adaptogens such as aloe, which improve our resilience to stressful situations, are great to add when one’s adrenals are feeling overwhelmed – and addressing adrenal issues can, in turn, help reverse many symptoms of Hashimoto’s! (Read more about adaptogens and adrenal health.)
Blood Sugar Balance
Aloe vera has been used as a remedy for elevated blood sugar levels. In one study, aloe vera was found to improve insulin sensitivity and fasting blood sugar levels in adults, when taken twice daily for 14 days. Not only did fasting blood sugar levels drop, but triglyceride levels (levels of fat in the blood, which are associated with type 2 diabetes) did as well.
This study suggests that aloe vera may help lower blood sugar levels, which are often found to be elevated in those with Hashimoto’s.
Infections
Studies have found that aloe vera is antibacterial and can prevent fungus and bacteria from multiplying within the colon.
Many antiseptic agents, such as salicylic acid, sulfur, and phenols, are found in aloe vera.
These antiseptic agents target bacteria, mold, viruses, and fungi – all of which can be root causes of autoimmunity. Aloe vera’s strong anti-viral properties have made it a particularly great option for various herpes viruses, including the Epstein-Barr virus, which are often triggers of Hashimoto’s.
Additionally, aloe vera contains numerous enzymes. These enzymes can help break up biofilms, which are densely packed colonies of pathogens that make their eradication difficult, even when using antimicrobial medications or herbs. The polysaccharide content from aloe vera has been shown to break up these biofilms as well as inhibit the binding of the bacteria Helicobacter pylori (often found in those with Hashimoto’s) to gastric cells.
While I feel there needs to be more research done on this plant and its biofilm-busting power, we do know that several pathogens can be triggering to Hashimoto’s, and often a biofilm agent is necessary, so aloe vera may help in this regard. You can read more about treating underlying infections to reverse Hashimoto’s here. When working with clients, I often see patients’ thyroid antibodies reduce when we treat underlying infections and pathogens.
Immune Health
The active compounds found in aloe vera have been found to have immune-modulating benefits.
An animal study published in the Journal of Pharmacology and Experimental Therapeutics evaluated extracted glycoproteins from aloe and found that they blocked antigen-antibody reactions (including the inhibition of histamine and leukotriene from mast cells), which are reactions that are produced when the immune system encounters foreign substances in the body.
Aloe’s naturally-occuring anthraquinone compounds (specifically, aloe-emodin) have also been shown to help inhibit the production of several proinflammatory cytokines (involved in inflammatory reactions) by white blood cells, when encountering pathogenic materials.
Polysaccharides (complex carbohydrates made of simple sugars), which make up 55 percent of the aloe vera plant, are also very beneficial to immune health. The polysaccharides acemannan and glucomannan, which are considered to be the two main active components of the plant, have strong antiviral and antibacterial components, as they stimulate white blood cells (which target infections).
Thus, the use of aloe vera can stimulate the immune system and be supportive to many people who have an underlying virus that is suppressing their immune system (and is at the root of their Hashimoto’s condition).
Oxidative Stress
One interesting study to note was published in the International Journal of Immunopharmacology in 1990. The study found that constituents found in aloe gel extracts can inhibit the release of reactive oxygen species (ROS).
ROS can have multiple effects within the body, including opening the gate for autoimmunity, and causing oxidative damage to our mitochondria and DNA. Oxidative stress results when there is an imbalance between ROS and antioxidants, as antioxidants counteract the harmful effects of ROS.
In Hashimoto’s thyroiditis, there is often an increased production of free radicals (toxic byproducts of oxygen metabolism), which may include ROS. Antioxidant capacity is also significantly lowered when one is in a state of autoimmunity. So, this study suggests that aloe vera may potentially help reduce oxidative stress and improve one’s autoimmune condition.
Read more about the importance of antioxidants in Hashimoto’s here.
Constipation
Due to the plant’s high polyphenol content, aloe vera is effective at relieving occasional constipation, which is a common symptom of low thyroid function. The anthraquinones present in aloe induce muscle contractions in the large intestine and have a laxative effect. Other plants also contain this organic compound, but aloe vera contains an especially large amount, with over 12 different anthraquinones.
Aloin, a type of anthraquinone derived from the yellow-brown sap in the outer leaf (also referred to as aloe latex, or Cape Aloes), increases muscular contractions and motility within the colon, resulting in softer stools. When taking aloe latex as a standalone for constipation relief, it is important to know the side effects and how long one should take this as a supplement.
Anthraquinones found in aloe latex increase fluid and electrolyte secretion into the GI tract, resulting in a bowel movement within ten hours. While I don’t recommend using it as a “laxative,” per se, some people do find that it helps with relieving constipation.
Again, since constipation is a common symptom experienced by those with hypothyroidism and Hashimoto’s, aloe vera may help be beneficial for some individuals.
It is also important to find the root cause of less frequent bowel movements, and I encourage you to do so. I’ll be coming out with an article on constipation in the future, but in the meantime, you may wish to consider testing for gut infections like H. pylori, SIBO, and Candida overgrowth, which are often underlying culprits behind constipation.
Supplementing with Aloe
There are various ways one can supplement with aloe, including juice, gel, powder, or capsule form.
In the above study, participants drank aloe vera leaf juice, at a dose of 50 mL, two times daily. It should be noted, however, that the juice form will contain the highest levels of anthraquinone compounds that will increase bowel motility and can cause a laxative effect, which can be a concern for some individuals, especially those who already tend to have loose bowels (of note, the Mayo Clinic doesn’t recommend using aloe as a laxative).
When my husband was having intense digestive issues in 2018 (a story for another day), I wanted to have access to an aloe formulation that didn’t cause more diarrhea and that could also be taken in powder or capsule form, as he didn’t like the taste of the liquids we had tried. This is how I decided to create the Rootcology Aloe capsules.
To make these capsules, aloe vera gel is rinsed to remove remnants of aloin (the laxative ingredient in the latex). I recommend one capsule per day of Aloe by Rootcology, which is highly concentrated. In fact, it takes 200 pounds of aloe vera gel to make one pound of this nourishing aloe extract! It is also prepared using a low-heat dehydration method with no filtering, which ensures that the plant’s beneficial components (long polysaccharide chains) and its natural makeup, remain intact as much as possible.
Here is what Roxanna S. had to say:
I have Hashimoto’s and I don’t digest things well. I’m trying aloe to help with my digestion and I feel like it is working well. I pair it up with bitters and digestive enzymes when necessary. I am not noticing the gas and bloating anymore.
Precautions
It’s important to note that some individuals may be sensitive to anthraquinone compounds, which are present in aloe latex (taken from the outer skin of the plant) and aloe whole leaf extracts. (Rootcology’s Aloe is tested for anthraquinone, and the content is below a detection limit of 0.1 ppm.) Due to its laxative effect, aloe latex may also cause a loss of minerals, such as potassium and sodium.
It is also important to note that one study reported the component aloin (found in aloe vera latex) to have carcinogenic activity. In this study, aloe vera (whole-leaf extract) caused intestinal irritation and acted as a carcinogen within the large intestine of rats. However, the concentration, as well as the strength, was over ten times the amount that someone would take in a daily dose, equaling a very high dose of 14.4 grams. Additionally, this study used whole-leaf extract (which contains the aloe latex from the outer rim, as well as the gel from the inside of the plant), which is different from the aloe vera that I recommend.
Aloe vera may also interact with certain medications. Avoid aloe if you are taking any of the following medications: anticoagulant/antiplatelet drugs, antidiabetic medications, blood thinners, corticosteroids (including prednisone and prednisolone), cardiac glycoside drugs (including digoxin and digitoxin), diuretic medications, sevoflurane, or stimulant laxatives.
There may be other medications that may interact with aloe, so please consult with your practitioner to review your current list of medications before starting supplementation.
Aloe vera should not be used by those who are pregnant or breastfeeding, diabetic, or have a bowel obstruction. Please check with your healthcare provider before using aloe vera if you have intestinal issues such as Crohn’s disease or ulcerative colitis.
As always, it is important to consult with a practitioner before starting this supplement, to ensure that it is right for you.
The Takeaway
In summary, aloe vera provides several essential vitamins, minerals, and amino acids. For some, the use of aloe vera may be beneficial for digestive symptoms such as reflux, a lack of digestive enzymes, and constipation.
It can also support liver and adrenal health, protect the body from infections, boost immune health, regulate blood sugar levels, and reduce oxidative stress.
If you have Hashimoto’s, aloe vera may be beneficial in eliminating symptoms, and supplementing with Rootcology’s Aloe and/or organic aloe vera juice could be a very helpful addition to your daily routine.
I hope this helps you on your health journey. Let me know if aloe vera has worked for you!
In the meantime, I invite you to check out my books Hashimoto’s: The Root Cause and Hashimoto’s Protocol for more information on how to address symptoms of Hashimoto’s and reverse the condition.
P.S. Be sure to sign up for my weekly newsletter to get a free book chapter, recipes, my Thyroid Diet Quick Start Guide, notifications about upcoming events, and my latest research.
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References
- Surjushe A, Vasani R, Saple DG. Aloe vera: A short review. Indian J. Dermatol. 2008;53:163166. doi: 10.4103/0019-5154.44785.
- Nahar T, Uddin B, Hossain S, Sikder AM, Ahmed S. Aloe vera gel protects liver from oxidative stress-induced damage in experimental rat model. J complement Integr Med. 2013. May 7;10. doi: 10.1515/jcim-2012-0020.
- Yongchaiyudha S, Rungpitarangsi V, Bunyapraphatsara N, Chokechaijaroenporn O. Antidiabetic activity of Aloe Vera L. Juice. I. Clinical trial in new case of diabetes mellitus. Phytomedicine. 1996 Nov;3(3):241-3.
- Xu C, Ruan XM, Li HS, Guo BX, Ren XD, Shuang JL, Zhang Z. Anti-adhesive effect of an acidic polysaccharide from Aloe vera L. var. chinensis (Haw.) Berger on the binding of Helicobacter pylori to the MKN-45 cell line. J Pharm Pharmacol. 2010;62:1753-1759.
- Nagpal R, Kaur V, Kumar M, Maratta F. Effect of Aloe Vera juice on growth and activities of Lactobacilli in-vitro. Acta Biomed. 2012 Dec;83(3):183-8.
- Parian A, Limketkai BN. Dietary Supplement Therapies for Inflammatory Bowel Disease: Crohn’s Disease and Ulcerative Colitis. Curr Pharm Des. 2016;22(2):180-188. doi:10.2174/1381612822666151112145033
- Bahrami G, Malekshahi H, Miraghaee S, et al. Protective and Therapeutic Effects of Aloe Vera Gel on Ulcerative Colitis Induced by Acetic Acid in Rats. Clin Nutr Res. 2020;9(3):223-234. Published 2020 Jul 30. doi:10.7762/cnr.2020.9.3.223
- Panahi Y, Khedmat H, Valizadegan G, Mohtashami R, Sahebkar A. Efficacy and safety of Aloe vera syrup for the treatment of gastroesophageal reflux disease: a pilot randomized positive-controlled trial. J Tradit Chin Med. 2015 Dec;35(6):632-6.
- Bugdaci M, Zuhur S, Sokmen M, Toksoy B, Albayrak B, Altuntas Y. The Role of Helicobacter pylori in Patients with Hypothyroidism in Whom Could Not be Achieved Normal Thyrotropin Levels Despite Treatment with High Doses of Thyroxine. Helicobacter. 2011;16(2):124-130. doi:10.1111/j.1523-5378.2011.00830.x.
- Metro D, Cernaro V, Papa M, Benvenga S. Marked improvement of thyroid function and autoimmunity by Aloe barbadensis miller juice in patients with subclinical hypothyroidism. J Clin Transl Endocrinol. 2018;11:18-25. doi:10.1016/j.jcte.2018.01.003
- Park MY, Kwon HJ, Sung MK. Evaluation of aloin and Aloe-emodin as anti-inflammatory agents in Aloe by using murine macrophages. Biosci. Biotechnol. Biochem. 2009; 73(4): 828-832.
- Â Ro JY, Lee B, Kim JY, Chung Y, Chung MH, Lee SK, et al. Inhibitory mechanism of aloe single component (Alprogen) on mediator release in guinea pig lung mast cells activated with specific antigen-antibody reactions. J Pharmacol Exp Ther. 2000;292:114-121.
- Hart LA, Nibbering PH, van den Barselaar MT, van Dijk H, van den Burg AJ, Labadie RP. Effects of low molecular constituents from aloe vera gel on oxidative metabolism and cytotoxic and bactericidal activities of human neutrophils. Int J Immunopharmacol. 1990;12:427-434.
- Resch U, Helsel G, Tatzber F, Sinzinger H. Antioxidant status in thyroid dysfunction. Clin Chem Lab Med. 2002;40:1132-1134.
- Davis RH, Parker WL, Murdoch DP. Aloe vera as a biologically active vehicle for hydrocortisone acetate. J Am Podiatric Med Assoc. 1991;81:1-9.
- Boudreau MD, Mellick PW, Olson GR, Felton RP, Thorn BT, Beland FA. Clear evidence of carcinogenic activity by a whole-leaf extract of Aloe barbadensis miller (aloe vera) in F344/N rats. Toxicol Sci. 2012;131(1):26-39.
- Lily of the Desert. The Aloe Vera Story. Lily of the Desert. https://lilyofthedesert.com/aloes-story. Accessed February 20, 2019.
Note: Originally published in June 2019, this article has been revised and updated for accuracy and thoroughness.
Wow, how exciting! I think I will start taking it. Dr. Wentz, do you happen to know what brand of aloe Vera the subjects took? Or could you perhaps recommend an acceptable/ effective brand that you have taken? Thank you much, ? Eneida
Eneida – you are very welcome! I am happy to give you the link to the Rootcology Aloe Vera that I recommend: https://rootcology.com/collections/supplements/products/aloe
Aloe seems to be contraindicated for SIBO and yet if it helps with constipation it could be helpful? Perhaps the pills would be safer but then they would not help as a laxative?
Julia – thank you for reaching out. Unfortunately, as a licensed Pharmacist, I am unable to legally provide specific medical advice here. Generally speaking, my clients have found success in treating gut infections through the use of antibiotics, herbal support, or a combination of both. Discussion of these options with your medical provider should be useful in determining the most effective course of treatment for you and should be based on your medical history, symptoms, and testing results. SIBO can take more than one round of treatment and requires retesting, you deserve the care of a focused primary care physician to advise you. I hope that you understand.
Here is an article I think you might find helpful.
COULD SIBO BE PREVENTING YOU REMISSION FROM HASHIMOTO’S?
https://thyroidpharmacist.com/articles/sibo-prevent-remission-hashimotos/
If you have C-diff biofilms still left in your intestine after a fecal transplant, can aloe juice taken at 50ml. twice a day cause these biofilms to activate? I have hypothyroidism and other conditions that could benefit from its’ use. Thanks, Pat
Pat – thank you for reaching out. I am so sorry you are struggling with this. Aloe Vera contains numerous enzymes and these enzymes can help break up biofilms, which are densely-packed colonies of pathogens that make their eradication difficult, even when using antimicrobial medications or herbs. The polysaccharide content from aloe vera has been shown to break up these biofilms as well as inhibit the binding of the bacteria Helicobacter pylori (often found in those with Hashimoto’s) to gastric cells. Here are some resources you might find helpful:
ROOTCOLOGY ALOE
https://rootcology.com/collections/supplements/products/aloe
ALOE VERA
https://thyroidpharmacist.com/articles/aloe-vera-thyroid-digestion-immune-support/
Great article on this topic. Thank you!
Dawn – you are very welcome! <3 I hope you will keep me posted on your thyroid healing journey!
Totally confused! Today I received an email stating that aloe Vera is not suggested to use if you have IBS, and from you saying it might be beneficial in healing Hashimoto’s and leaky gut! I’m not sure if I should try it or not!!
Ruthie – thank you for reaching out. I am so sorry you are struggling with IBS. <3 I’ve found that many Hashimoto's patients also have the gut infection Blastocystis hominis, which has recently been connected to irritable bowel syndrome, hives AND Hashimoto’s. In the last few years, I’ve noticed that getting rid of the Blastocystis hominis infection can help people to get their Hashimoto’s into remission. Read more about it in my Blastocystis article: A COMMON ROOT CAUSE OF HASHIMOTO'S, HIVES AND IBS
https://thyroidpharmacist.com/articles/the-common-root-cause-of-hashimotos-hives-and-ibs
Does using it topically have any of the same effects?
Alex – thank you for reaching out. Aloe vera has numerous healing benefits when taken both orally and applied topically. I have not personally researched whether you would get the same benefits from using it topically. 🙂 I would love to hear more about your experiences here on this page!
Hi Izabella,
I can not thank you enough for all your work.
Aloe gel applied topically is magic for sunburn. I cut the leaf and ‘butterfly’ it and then rub the inside of the leaf gently onto sunburn. I’ve used this successfully for over 15 years for myself and my fair skinned family living in a hot climate.
Mel – thank you so much or sharing! ❤️
Hi Izabella,
I love your posts and find your books so informative and supportive.
I have one question about Aloe Vera. If serum free T3 declines by 16% should those of us who may have a problem with conversion of T4 to T3 approach using it with caution?
Thanks,
Patricia
Patrica – thank you for your following this page! <3 Aloe Vera contains minerals and trace minerals which are vital for thyroid protection and a healthy conversion from T4 to T3. That said, I always recommend that you discuss the use of any supplement with your practitioner who knows your health history.
Dear Dr Wentz,
Hi, I cannot thank you enough for the valuable resources and information you provide.
I wanted to post this on the recent male/Father’s Day post but did not find the time.
I was diagnosed with Hashimoto’s 30 months ago at the age of 34. This was a massive surprise to me, I feel like mentally I still have not accepted this fully. My TSH was 272 with a T4 of 4. I am based in the UK. The results were also a surprise to my doctor as I did not look like your typical ‘hypothyroid’ patient and they had not seen such a deranged TSH before.
The main symptoms I had were; crippling health anxiety, visual disturbances, noticeably cold hands, neck aches and a prolonged bout of palpitations – which prompted the investigations uncovering my diagnosis.
As someone who has always been very strong, athletic, conscious of my diet and health-this was a massive blow; I felt ashamed and a failure, I still have not told some of my friends or work colleagues but plan to change this soon and be more open.
At the time my doctor was unsure of the cause, given I was not your textbook hypothyroid patient, young male, not overweight and looked relatively well – however this uncertainty made me ill with worry. With my TSH level my doctor felt it may have been a pituitary problem and arranged MRI scans etc which made me constantly fear the worst. The lack of understanding from my doctor, although very well intentioned and lack of communication made this a terrible period personally and I became very fearful for my own and my families future.
At this stage I was frantically searching for trustworthy sources of information, thankfully I landed on your work and could see the effort, research and sincerity behind it all. It was so reassuring to find someone who is clearly absolutely genuine in their desire to help as many people as possible; your advice has helped me to feel better and provided me reassurance, guidance and much needed hope at a very dark time.
I am sharing specific personal details on the chance anyone recently diagnosed, with some quite deranged numbers and reading this does not panic themselves into an absolute frenzied mess like I did!
Dr Wentz I was wondering if you have any resources/advice regarding fasting/intermittent fasting? I have read information outlining this may be beneficial for autoimmune conditions but no information specifically regarding the benefits and safety implications relating to Hashimoto’s. Thank you so much for all that you do.
Mike
Mike – thank you so much for reaching out and sharing your journey. <3 While fasting can be beneficial in many cases, some caution is required for people with Hashimoto’s due to our blood sugar issues. Blood sugar imbalances are a big contributor to Hashimoto’s. Balancing blood sugar levels should be one of the priorities for anyone who is hoping to overcome autoimmune thyroiditis and adrenal fatigue. Balancing my blood sugar made a big difference for me, helping with my anxiety levels and reducing my thyroid antibodies. I hope these articles help shed some light on the matter:
BLOOD SUGAR IMBALANCES AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/blood-sugar-imbalances-and-hashimotos
What effect does taking aloe vera have on hyperthyroidism?
Jane – thank you for reaching out. <3 Graves and Hashimoto's are both autoimmune conditions that affect the thyroid. They are thought to be closely related. Sometimes one turns into the other. The difference is the site of the antibody attack. In Hashimoto's, the antibodies are found to thyroglobulin (in 80%) and thyroid peroxidase (TPO) enzyme (in 95% of people) Hashimoto's results in hypothyroidism and is usually treated with Synthroid and replacement hormone.
The same antibodies may be present in a smaller percentage of people who have Graves, but the main antibody is to the TSH Receptor (TSHR-Ab). Usually, people with Graves have hyperthyroidism, and they are treated conventionally with thyroid suppressing drugs (methimazole) or radioactive iodine to destroy the thyroid. At that point, the thyroid will no longer produce hormones on its own, and these people end up on Synthroid as well.
Most thyroid conditions result from the immune system attacking the thyroid because the immune system is out of balance. Even when the thyroid is taken out surgically or treated with radioactive iodine the autoimmunity still persists in most cases. Many people will have their thyroids removed, and will develop new autoimmune disorders such as Lupus, Rheumatoid arthritis, etc. The immune system just finds a different target.
We need to rebalance the immune system to prevent this. Sometimes the autoimmunity can be reversed as well! The gut determines your immune system. With the exception of discussing proper thyroid medication dosing, the majority of my website and my book focuses on balancing the immune system. The info I present is based on my own research and journey for overcoming my autoimmune thyroid condition. Here are the links to my books:
Hashimoto’s Root Cause
http://amzn.to/2DoeC80
Hashimoto’s Protocol
http://amzn.to/2B5J1mq
Hashimoto’s Food Pharmacology
https://www.amazon.com/Hashimotos-Food-Pharmacology-Nutrition-Protocols/dp/0062571591?tag=thyroipharma-20
I have been taking Aloe Vera for years before bedtime for my acid reflux, just a swallow or two. I have not had a problem since. I did not realize that it was also helping other things as well.
Patricia – thank you so much for sharing how Aloe has worked for you! <3
So by taking a Aloe Vera supplement, would this then stop the need to also take a magnesium supplement and a zinc supplement etc?
Lynda – thank you for reaching out. <3 Please understand, I am not able to advise what supplements and combinations would be appropriate for you and your specific health needs without a comprehensive health assessment. I recommend that you discuss this with your personal doctor. <3
Wow, so many benefits here. I have the barbadensis variety, I got it with the intention to do something with it to help my health and Hashimoto’s. I have never done anything with it though as I have no idea where to start. Any tips please?
K – thank you so much for reaching out. There are various ways one can supplement with aloe, including juice, gel, powder, or capsule form. recommend one capsule per day of Aloe by Rootcology, which is highly concentrated. In fact, it takes 200 pounds of aloe vera gel to make one pound of this nourishing aloe extract. It is also prepared using a low-heat dehydration method with no filtering, which ensures that the plant’s beneficial components (long polysaccharide chains) and its natural makeup, remain intact as much as possible. I hope you check out the article for more information about Aloe:
https://thyroidpharmacist.com/articles/aloe-vera-thyroid-digestion-immune-support/
Hello, thank you for your articles! They are very helpful since my diagnosis last year. I am struggling with self healing and lack of support from the health care field. I look forward to trying Aloe and was wondering how long to take it for? Is it something to take everyday for the rest of my life or short term?
Jen – thank you for reaching out. I am so sorry to hear you are struggling. <3 You should start with the directions on the bottle and adjust from there. Please understand I am unable to answer specific medical questions without a comprehensive health assessment. If you have more specific questions on how and when to take the Aloe under normal circumstances, please do reach out to my team by email, at info@thyroidpharmacist.com and they will be more than happy to help ?
If one is hypoglycemic, would aloe be safe as it works on blood sugar? Or does it just work on elevated levels, but won’t take regular levels too low?
Stacy – thank you for reaching out. Please understand, with out a comprehensive health assessment I am not able to advise whether Aloe would be appropriate for you and your specific health needs. I recommend that you discuss this with your practitioner. <3
Is aloe safe to take long term? My health provider had prescribed some Aloe for me that says on the bottle, “For occasional use only.” It is Cape Aloe, so maybe that has something to do with why it would only be for occasional use? Your article is interesting because the aloe I’ve been taking has been having an overly-laxative effect. So maybe if I switch to the aloe juice extract type, it would have less of a laxative effect while still giving me the other benefits? I appreciate all of the information you share!
Brittany – thank you for reaching out. For specific questions about the supplements please email my team at info@rootcology.com and they will be happy to help you. <3
Dear Dr,
Thank you for so much information. I am a patient of hypothyroidism with TSH value 9.9. rest values T3 and T4 are normal. I am taking medication from last five months.can I take aloe vera juice after two hours of taking thyroid medicine. I am bit confused as it contains small amount of calcium.
Aditi – thank you so much for reaching out and sharing your journey with me. For specific questions about the supplements please email my team at info@rootcology.com and they will be happy to help. <3
I am really excited by this news, I have purchased some aloe vera juice from amazon, what is the best way for me to take it? I take 100mcg T4 at night and 12.5mcg T3 in the morning and another 12.5 at 1pm. Thanks for all your help.
Ian in the UK
Ian – thank you for reaching out. For questions about the supplements please email my team at info@thyroidpharmacist.com and they will be happy to help. <3
Dear Dr. Wentz,
Could you possibly suggest effective brands of aloe juice? living in a very small and very remote place make it next to impossible to utilize any source other than bottled. most all those have preservatives. there are two of us in this household who need aloe apparently, and I sure would like to get started… if I know what to look for.
Thanks so much for your help, and for your books and for all you do!
Kate – thank you for reaching out and sharing. <3 Here is a link to the Aloe vera juice that I recommend in the article:
https://www.amazon.com/gp/product/B0011DMYMC/ref=as_li_tl?imprToken=YCm-wvgFEVyQQv4DfO1Ssw&slotNum=1&ie=UTF8&tag=thyroipharma-20&camp=1789&creative=9325&linkCode=w61&creativeASIN=B0011DMYMC&linkId=3addebff56b8953af33f62ec063ef8f9
I have greatly benefited from your Hashimotos Protocol and Cookbook. I have had very good results from your Benfotiamine and Selenium supplements. For years I have had a functional medicine practitioner helping me with my thyroid Hashimotos issues. Now my husband and I have had to go on a Medicare HMO due to reduced income in retirement. I lost my functional medicine doctors and have had to be my own doctor . For years I have been drinking distilled aloe vera juice for leaky gut which has almost totally resolved itself. Still some minor problems when I eat allergic foods but nothing like in the past. I did not even consistently take the aloe vera but always loved the way it just made all my gastro tract feel soothed. So excited to see the news about the juice in relation to Hashimotos! I am just concerned about taking the whole leaf aloe because I am taking the distilled version due to the issue that the whole leaf version was harder on the gut and I did not have constipation problems, but the opposite with leaky gut. I am so much better with my gut now, one to two regular movements every day. I had no idea that it was probably the aloe that was helping me so much. I am concerned still about taking the whole leaf aloe but you do not address the existence of the distilled version. Will it give me the all the other benefits if I continue it?
Rebecca – Thanks for writing in! Unfortunately, I am not aware of studies related to distilled aloe vera juice, so I cannot vouch for its effectiveness as the distilling process may affect the aloe vera’s properties. <3
What Aloe juice is good to drink
Claudette – thank you for reaching out. Here is a link to the aloe juice that I recommended in this article:
https://www.amazon.com/gp/product/B0011DMYMC/ref=as_li_tl?imprToken=ac23mU6-TFUWxWZa0NC33A&slotNum=0&ie=UTF8&tag=thyroipharma-20&camp=1789&creative=9325&linkCode=w61&creativeASIN=B0011DMYMC&linkId=3addebff56b8953af33f62ec063ef8f9
Great article and Aloe seems to have many benefits. The potassium depletion is a concern. As a result of reading your books I am now drinking a cup of warm lemon water before my bulletproof coffee. Then I take my Selenium with vitamin E about 15 minutes or so after taking my thyroid medicine. Should I discontinue taking the Selenium and E if I switch and take your Aloe vera supplement.
Leina – thank you so much for reaching out. Please understand, I am not able to advise on whether this supplement would be appropriate for you and your specific health needs without a comprehensive health assessment. It’s always best to discuss any supplement addition with your practitioner. <3
I have also read that the inner leaf juice of the aloe plant is also great for kidney issues in a cat. The 2 tests between diagnosis and getting my cat’s kidney medications had her kidney numbers drop dramatically. The vet said whatever you’re doing, keep doing it. The outer leaf is toxic to cats. Sounds like it may be to humans as well. May try it now for myself. Thanks for all the great info! : )
Andrea – thank you so much for sharing! <3
Hi Dr. Wentz!
In 2011 when first diagnosed with Hashimoto’s my antibodies
were 750 . LDN was prescribed along with armour thyroid. Made dietary changes back then, and thyroid antibodies dropped to around 140. Couldn’t tolerate LDN and antibodies began to rise. Have always been a root cause seeker for my disease. Discovered you and ordered Root Cause. Got of iodine ( which had been prescribed) and started selenium and was on many of the supplements already, that you had recommended. My antibiotics began to fall dramatically. As of May 15th, 2019, my TPO ab is 60, Thyroglobulin Antibody is 1.0 and free T-3 is 3.9 and this is after reducing my Liothyronine from 25 to 20 mcg. So thyroid function is improving.
I got very sick with what seemed to be the flu, this past Feb. Started having severe major hives after flu, upon eating. My thyroid antibodies where dropping even in the midst of hives. Went on a low histamine diet, and still severe excruciating hives all over my entire body would occur. Massive welts. Horrible. Asked for parasite test to be done and tested very positive for Canine Dipylidium – Tapeworms that are common to dogs. No blasto, giardia or any other parasites thank God. Just some vicious Tapeworms. Got to see slide with my own eyes, which was very cool. Doctor is a parasite specialist. Was put on a course of Praziquantel, and herbals Mimosa Pudica seed, Rain Forest AP, and I added neem and cloves. On the herbals for 3 additional months. Can now eat majority of foods that I had to eliminate. Had also really been working on healing my gut prior to parasite infection. I feel that I am clear of the TW. But must still have some damage to my gut lining from the infection. Some times have these hives sporadically. Not as severe as when I had TW. My practioner feels it is gut lining related from the infection. I have been L- Glutamine, 10 mg for well over two years and a really good probiotic for past 2 years, also bone broths, Chicory root tea, passion flower mixed with Tumeric/ Ginger golden paste- hot drink I make with almond milk. No sensitivities to almond milk. Also have been on quercetin and stinging nettle extract, vital -C /lipisomal. Even more improvment with that. Also read about boosting DAO enzymes to break down histamines. Started taking 2 tables extra virgin olive( high in oleic acid) oil in divided dosage last couple of days. Had read that by increasing DAO that break down histamines in the gut, Olive oil was top on list. Following that food list too. Pretty much foods that you too have recommended for Hashimoto’s. Even more improvment with the sporadic small hive out breaks, since starting olive oil.
I just read your article on the aloe without the aloin. I am going to start taking to see if this will further heal my gut and help with hives and also antibodies. Animals like dogs or cats are now a trigger, if I go into a home that has animals. Never had this issue with going into a home with animals.
Amazingly, like mentioned my antibodies continued to drop even before the parasite ok infection was diagnosed. Practioner shocked about that.
I know that the changes that I according to your book is certainly a huge part is what has helped me.
So hoping the aloe supplementation will help even more.
Should I take the aloe caps on empty stomach, just 500 mg once a day. How far out should I space it from thyroid meds or supplements?
Thank you Dr. Wentz! Love all of your emails and articles.
Kim – thank you so much for sharing your journey with me. I am so proud of your for taking charge of your health! ❤️ I recommend one capsule per day of the Rootocology Aloe. It is highly concentrated. If you have more specific questions on how and when to take the Aloe supplements under normal circumstances, please feel free to reach out to my team by email, at info@thyroidpharmacist.com and they will be more than happy to help.
Thank you Dr. Wentz!
Kim – you are very welcome!
Hi Kim! I am wondering how you felt taking the praziquantel with hashimotos? Did it cause any flares of your thyroid? I am set to start a similar course for same reason and am curious if it effects thyroid and causes any type of storm.
The healing process is a long journey!
Hi,
Thank you for the profer article above. Is this aloe workable during the pregnancy period ? And how effective for the skin spots/ sunburns spots?
Thanks for all your help !
Sinion – thank you for reaching out. <3 Aloe vera is not recommended to be taken orally during pregnancy, as it can potentially act as a uterine stimulant during pregnancy. It also should not be used orally when breastfeeding, as some of the active compounds can be secreted through breast milk. If you have an other questions about the supplements please feel free to email my team at info@rootcology.com and they will be happy to help.
I’ve never heard of vitamin B12 being in a plant source. Can you tell me where you found that out?
Valerie – thank you so much for reaching out. <3 Aloe is one of the few plants that does contain B12. Here's a study I hope you find helpful: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763764/
Love your article on Aloe Vera. I need to daily start taking it again.
Thank you. What products do you suggest? Otherwise I buy the gallon at Trader Joes that looks like water.
Thanks.
Helen
Helen, thank you so much! <3 I hope you will check out the article above for my recommendations!
i have nodules on thyroid will this aloe work to dissolve them for good.
Anita – thank you for reaching out. ❤️ Nodules and goiters are often the result of toxicity and/or the autoimmune process. So, doing interventions to reduce the autoimmune attack on the thyroid, and toxicity, can be helpful to reduce them. Here is an article you may find helpful.
THYROID NODULES
https://thyroidpharmacist.com/articles/hashimotos-and-thyroid-nodules/
Will it help hypothyroid patients loose weight
Joann – thank you for reaching out. ❤️ When it comes to weight gain these are a couple of things to think about.
1) What was your recent TSH, Free T3 and Free T4? Sometimes when those numbers are on the outskirts of normal, your metabolic rate may still be impaired making it more difficult for you to burn calories. Most people report feeling well with a TSH between 0.5-2.
2) What type of medication are you on? Some report more weight loss with T4/T3 combinations (Armour, Nature-Throid, compounded medications) versus T4 medications (Synthroid, Levoxyl, Tirosint) alone. T4 is a precursor to T3, but some individuals do not convert T4 to T3 properly, and the T3 component is the metabolically active one.
3) What type of diet are you eating? Some report more weight loss with T4/T3 combination vs T4 alone. Some do not convert T4 properly.The Standard American Diet (S.A.D.) full of sugar and simple carbohydrates is perfectly designed to cause us to gain weight year after year. Even yogurts that are marketed as “healthy” contain the equivalent of 16 teaspoons of sugar. Divorcing the S.A.D. is often a step that many of us must take to not just lose weight, but to also feel better. Some diets that have been helpful include the Body Ecology Diet, the Paleo Diet, the Virgin Diet, Autoimmune Paleo Diet, GAPS diet, SCD diet, Weston A. Price Diet, or the Mediterranean Diet. You may need to modify these diets to your own individuality.
BEST DIET FOR HASHIMOTO’S AND HYPOTHYROIDISM
https://thyroidpharmacist.com/articles/best-diet-for-hashimotos-hypothyroidism
HOW TO LOSE WEIGHT WITH HASHIMOTO’S AND HYPOTHYROIDISM
https://thyroidpharmacist.com/articles/how-to-lose-weight-with-hashimotos
If you supplement with aloe for a period of time, let’s say 6-9 months, and see your numbers get better, what happens if you stop taking aloe? Do your numbers stay the same or go back to being worse without daily consumption of aloe? Also if you are taking medication and start supplementing with aloe, do you have to test and potentially decrease medication due to the aloe’s beneficial affect?
Sarah – thank you so much for following. We all react differently. When it comes to testing, I always recommend working with a functional medicine practitioner or a doctor, who can closely monitor your medication dosage and advise you throughout the protocols. Every six weeks is usually a good schedule for testing your thyroid hormones. ❤️
Hello!
I have been diagnosed with Hashimoto’s since 2009. I have been taking aloe vera past 5 months already and I took TSH test today that shows 10.1. I feel okey of course I was expecting my TSH to be normal. Now my question is is there a possibility that my Thyroid gland is irreparably damaged? Bare in mind that the trigger of all this was mercury poisoning back in 2007 since then I have had several issues the main one being diagnosed hashimoto’s. So really I need to know if I continue with aloe vera till 9 months or give up? Thanks.
Max – thank you for reaching out and sharing. <3 When it comes to the Aloe I am not able to advise you with out a comprehensive health assessment. I recommend that you discuss this with your personal doctor. As for you question about you thyroid, Thyroid tissue can regenerate, but the rate at which it does is not always predictable. Thus, some are able to stop the autoimmune attack on their thyroid and regain normal thyroid function. Others can reduce the dose of medications, and others will need to stay on the medications indefinitely. Reversing Hashimoto's means different things to different people. For some, it means a reduction in symptoms, and for others, it means a reduction in your antibodies. I had both. Here are few articles that might be helpful for you:
IS IT POSSIBLE TO RECOVER THYROID FUNCTION IN HASHIMOTO'S
https://thyroidpharmacist.com/articles/is-it-possible-to-recover-thyroid-function-in-hashimotos
REVERSING AUTOIMMUNITY? AND THE PERFECT STORM
https://thyroidpharmacist.com/articles/reversing-autoimmunity-and-the-perfect-storm/
Given the high selenium content of aloe, would taking an aloe supplement replace my selenium supplement?
Stephanie – Great question! ❤️ The amount of selenium in aloe may vary per product, and while it may be supportive, is not likely to be a therapeutic dose. I generally recommend supplementing with selenium, to ensure a consistent and therapeutic dose (200 mcg/day of selenium is the dose that has been most well-studied in Hashimoto’s). I hope that helps!
I am curious why diabetics shouldn’t take aloe vera? Especially since it helps with blood sugar.
Sarah – thank you for reaching out. ❤️ Aloe can interact with certain medications including antidiabetic medications.
Thank you for the great research article! Out of curiosity, can we simply start eating our aloe plants rather than use supplementation? If so, how would we prepare it?
Kristie – thank you for reaching out. ❤️ That is something I have not researched this. I recommend finding a reputable brand that is organic. I shared some recommendations in the article above.