Three Factors Need to be Present for Autoimmunity to Develop
There is not just one event that causes autoimmunity, but instead, a series of events has to line up just right to create the perfect storm, or perfect circumstances, for developing autoimmunity.
Recent advances in autoimmunity have been made by an American researcher Alessio Fasano.
Dr. Fasano and his colleagues have suggested that there are three factors that need to be present for autoimmunity to develop:
- Genetic predisposition
- Exposure to antigen (trigger)
- Intestinal permeability
The intestinal permeability and triggers cause an immune system imbalance that results in the body no longer recognizing itself from a foreign invader.
It was once believed that once the autoimmune process is activated, it becomes independent of continuous exposure to the environmental trigger and becomes self-sustaining and irreversible.
However, examples of autoimmunity have discredited the “irreversible” aspect of this theory. It has been shown that continuous environmental triggers are necessary to perpetuate the process. This means that the autoimmune process can be stopped and reversed when the triggers are eliminated. One example of this is celiac disease, an autoimmune condition where gluten, an environmental trigger, has been identified. In most cases of classical celiac disease, all symptoms resolve when the environmental trigger (gluten) is removed.
Another aspect we can impact is the intestinal permeability. Sometimes the permeability is a result of the trigger, other times it is independent of it. It sounds really simple right?…the tricky part is figuring out your triggers…that’s what I’ve spent the last few years working on…
How To Find Your Path
Healing from any chronic condition and moving towards better health is a journey. You may stumble before you succeed. I know that I struggled for a few years before I finally found what worked for me.
“Every strike brings me closer to a home run.” – Babe Ruth
I was so encouraged to hear wonderful things about people eliminating thyroid antibodies through gluten free, dairy free, and Paleo diets, but while helpful, this did not result in an elimination of thyroid antibodies for me.
I had to continue to peel back layers, to dig deeper to get at the root cause of my condition…
I was so frustrated and nearly gave up, but now I understand that perhaps I struggled so that I could, in turn, help others with my DIG AT IT approach.
Don’t Give Up, Dig At It!
How do you find the root cause of your autoimmune condition? You have to DIG AT IT™. Once you do, you will know what types of changes you need to implement to make yourself feel better.
DIG-AT-IT stands for the following:
- Inflammation, Immune Imbalances, Infections
- Gut, Gluten
- Adrenals, Alkaline Phosphatase
These are all factors that contribute to autoimmunity! It seems that not everyone may have the same issues present…
I have just finished writing a book on finding and treating the root cause of Hashimoto’s using the DIG AT IT approach and lifestyle interventions….I hope that my book and blog will guide and inspire others to find their own root cause and take on lifestyle interventions that will be helpful for them.
I work full time as a pharmacist, so it hasn’t been that easy to write the book and get better all at once while keeping up with my other priorities. My next goal is to build this blog to help spread the word. I have now learned that it’s not that easy to summarize the information from a 340-page book into one blog post at a time effectively,..but I will try 🙂
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I have started off writing about Nutrient Depletions and will be blogging about the different headings over the next few months.
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NOTE: These statements have not been evaluated by the Food and Drug Administration. The products discussed are not intended to diagnose, treat, cure, or prevent any disease.
The medical information in on this blog is provided as an educational resource only and is not intended to be used or relied upon for any diagnostic or treatment purposes. This information should not be used as a substitute for professional diagnosis and treatment.
Please consult your health-care provider before making any healthcare decisions or for guidance about a specific medical condition.
I wish you all the best in your healing journey!
PS. You can also download a free Thyroid Diet Guide, 10 Thyroid friendly recipes, and the Nutrient Depletions and Digestion chapter for free by going to www.thyroidpharmacist.com/gift. You will also receive occasional updates about new research, resources, giveaways and helpful information.
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