Molecular Mimicry—An Autoimmune Theory
Molecular mimicry is the theory that bacterial cells or other microbial “triggers” have a similar appearance to the cells that make up parts of our physiology or “self” antigens.
When an infection occurs, these infectious cells are recognized as foreign. This is really great for getting rid of the infections, but sometimes the immune system targets proteins in the infectious cells that resemble the proteins in our own cells. This inadvertently causes a cross-reaction with our “self” antigens, i.e., our own cells. This case of mistaken identity is thought to trigger the start of autoimmunity.
One example is Streptococcus pyogenes. This is the bacteria that causes the common throat infection known as “strep throat.” In some cases, especially when the infection is not treated with antibiotics within two to three weeks, the immune system will start launching an attack against the Streptococcus bacteria.
Unfortunately, a component of the bacteria’s cell wall resembles that of the human heart valves, and this results in the immune system attacking the human heart valves in a case of mistaken identity. This reaction is known as rheumatic fever and can be deadly, and often necessitates heart valve transplants. Arnold Schwarzenegger is probably the most well-known person who was affected with this condition and has had to have heart valve transplants as a result.
Which Bacteria Have Been Associated with Triggering Hashimoto’s?
A variety of bacterial infections have been implicated in triggering autoimmune thyroiditis, including Helicobacter pylori (the same bacteria that causes ulcers), Borrelia burgdorferi (associated with Lyme disease), and Yersinia enterocolitica.
Antibodies to Yersinia (indicating exposure) in people with Hashimoto’s were found fourteen times more often than in people without Hashimoto’s. Yersinia membranes contain a site that binds TSH, making it a prime suspect based on the molecular mimicry theory. Infection with this bacteria can induce antibodies against sites that recognize and stimulate TSH receptors, like the thyroid peroxidase enzyme or thyroglobulin.
People can contract a Yersinia enterocolitica infection from contaminated meat, poultry, dairy products, and seafood (especially oysters). In 2012, a consumer group found that 67 percent of pork sold in the U.S. was contaminated with Yersinia!
Testing
Physicians can run blood tests, stool antigen or breath tests for H. pylori. If you cannot find a physician that will run the test for you, you can also order your own labs tests via direct-to-patient lab testing that I have set up through three channels: Rupa Health, Direct Labs, and MyMedLab (you can find a list of specific recommended lab tests for different infections here). You can find a practitioner near you who believes in the root cause approach by downloading my free guide here.
Borrelia detection is available as a blood test, while the presence of Yersinia can be tested by a comprehensive stool analysis. You will need to request Yersinia to be added to the test panel.
Treating Infections
New autoimmune theories have established that once the antigen (trigger) is removed, the antibody production goes away and the innocent part of our bodies (in the case of Hashimoto’s, the TPO enzyme) is no longer a target.
In the case of infections, once the infection is removed, the TPO enzyme should no longer be a trigger once the immune system recognizes that the infection is gone. Thus, treating infections may help to heal Hashimoto’s. In other cases, the infection may be gone and the immune system may need a reboot.
Antibiotics for Autoimmune Conditions?
Some individuals have reported the normalization of thyroid peroxidase antibodies following taking the antibiotic doxycycline, which is effective for Yersinia enterocolitica and Borellia burgdorferi, as well as other bacteria.
Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There are a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day, so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
Treatments for H. Pylori
H. pylori is a stubborn infection. Standard medical treatments for H. pylori include:
- Triple therapy: Two antibiotics: Amoxicillin or metronidazole plus clarithromycin, with a proton pump inhibitor (While proton pump inhibitors can make us more susceptible to H. pylori by themselves, they work in synergy with antibiotics to reduce H. pylori.)
- Quadruple therapy: Pepto Bismol + tetracycline + metronidazole + proton pump inhibitor
Some individuals may be hesitant to try antibiotics. Integrative clinicians have reported much success with using natural remedies like the ones listed below:
- Probiotics and fermented foods like lacto-fermented sauerkraut
- Extra-virgin coconut oil
- Whole cloves of garlic
- Fermented foods
- Glycyrrhizin (licorice)
- Quercetin
- N-acetyl cysteine
- Coenzyme Q10
- Turmeric
- Oil of oregano
- Aloe vera juice
- Mastic gum
Note: Not everyone will test positive for one of these infections; not everyone will be helped by doxycycline or the natural substances I listed. These are just a few of the things that could be at the root cause of Hashimoto’s… There are many other triggers…
If there is a pressing issue for you, send me a message or leave a comment. I am here to help.
If you are new here, here are some other posts you may be interested in:
- Reversing Autoimmunity
- What’s Really Going On in Hashimoto’s
- Is It Possible to Recover Thyroid Function in Hashimoto’s
NOTE: These statements have not been evaluated by the Food and Drug Administration. The products discussed are not intended to diagnose, treat, cure, or prevent any disease.
The medical information on this blog is provided as an educational resource only and is not intended to be used or relied upon for any diagnostic or treatment purposes. This information should not be used as a substitute for professional diagnosis and treatment.
Please consult your health-care provider before making any healthcare decisions or for guidance about a specific medical condition.
PS. You can also download a free Thyroid Diet Guide, 10 thyroid-friendly recipes, and the Nutrient Depletions and Digestion chapter of my first book for free by signing up for my weekly newsletter. You will also receive occasional updates about new research, resources, giveaways and helpful information.
For future updates, make sure to follow us on Facebook and Instagram!
References
- Rojas M, Restrepo-Jiménez P, Monsalve DM, et al. Molecular mimicry and autoimmunity. J Autoimmun. 2018;95:100-123. doi:10.1016/j.jaut.2018.10.012
- Guilherme L, Faé KC, Oshiro SE, Tanaka AC, Pomerantzeff PM, Kalil J. Rheumatic fever: how S. pyogenes-primed peripheral T cells trigger heart valve lesions. Ann N Y Acad Sci. 2005;1051:132-140. doi:10.1196/annals.1361.054
- Figura N, Di Cairano G, Moretti E, et al. Helicobacter pylori Infection and Autoimmune Thyroid Diseases: The Role of Virulent Strains. Antibiotics (Basel). 2019;9(1):12. Published 2019 Dec 30. doi:10.3390/antibiotics9010012
- Benvenga S, Santarpia L, Trimarchi F, Guarneri F. Human thyroid autoantigens and proteins of Yersinia and Borrelia share amino acid sequence homology that includes binding motifs to HLA-DR molecules and T-cell receptor. Thyroid. 2006;16(3):225-236. doi:10.1089/thy.2006.16.225
- Vojdani A. A Potential Link between Environmental Triggers and Autoimmunity. Autoimmune Dis. 2014;2014:437231. doi:10.1155/2014/437231
Note: Originally published in February 2015, this article has been revised and updated for accuracy and thoroughness.
Mundana says
What I don´t understand is why to use a Proton Pump Inhibitor to make the stomach less acidic, as I have read that h. Pylori lower itself the stomach acids and this is why we have digestion issues.
Also I wanted to ask you if you have heard that magnetic therapy can kill bacterias without harming our body. it mainly consist on being putted some magnets on our body by a specialist in this therapy. Could it be truth?
Dr. Izabella Wentz says
Mundana- I highly recommend that you work with a functional medicine clinician. It’s a whole medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms.
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
CLINICIAN DATABASE
http://www.thyroidpharmacistconsulting.com/clinician-database.html
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://www.functionalmedicine.org/practitioner_search.aspx?id=117
Cindy says
I have been going
sasha says
Dr. Izabella Wentz says
Sasha- Here is an article you may find interesting! 🙂
INFECTIONS AS HIDDEN TRIGGERS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/infections-as-hidden-triggers-for-hashimotos
HASHIMOTO’S AND THE GUT
https://thyroidpharmacist.com/articles/hashimotos-and-the-gut
Bet says
Melanie says
Bet, i was confused after having taken the antibiotic a proton pump inhibitor(which by the way I am and was totally against them wish I would have taken time to find a natural way to kill the h pylori) for my H pylori infection. Because about 7 days into the 14 days of treatment I started to have pain in my right arm from the top of the arm to the tip of my middle finger. I quit taking the proton pump inhibitor because I started researching on the round of medicine for the infection. Also found a book by Jonathan Wright called why we need stomach acid and he went into great detail about h pylori infection and how to get rid of it. Anyways back to what I was saying about my arm, I have had joint problems in my middle finger on that side since overtime I eat something that is inflammatory. I didn’t have these issues prior to taking these meds so I think that they triggered an auto immune onset for me. So if possible I would suggest people to try the natural herbs first. Our bodies are already compromised with the infection and then we take the round of antibiotics with the proton inhibitors and in some cases this can be the onset of auto immunity.
I agree with you that the infection causes low stomach acid so why have to take it orally with the meds??
Dr. Izabella Wentz says
Melanie – thank you for following this page and for sharing.
I highly recommend that you work with a functional medicine clinician. It’s an entire medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms.
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
CLINICIAN DATABASE
http://www.thyroidpharmacistconsulting.com/clinician-database.html
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://www.functionalmedicine.org/practitioner_search.aspx?id=117
Izabella Wentz, PharmD says
I would usually try natural therapies for H. Pylori, like mastic gum, but providing the info about the meds for those that do not benefit from herbals or prefer the RX route.
I also agree with you on the low stomach issue. I am very much against using PPI’s for acid reflux, as I believe that most of us do have low stomach acid. Additionally, and H. Pylori infection lowers our stomach acid further!
Thank you for keeping me on my toes, I will clarify the blog post accordingly 🙂
Angeline says
Izabella Wentz, PharmD says
Angeline says
Izabella Wentz, PharmD says
Melanie says
Hi Izabella, I was wondering what brand of mastic gum you recommend? Also how much of a dosage?
Dr. Izabella Wentz says
Melanie – thank you for following this page.
I cover Mastic Gum dosing in my book on page 314 of Hashimoto’s Protocol. Have you taken a look?
Hashimoto’s Protocol
thyroidpharmacist.com/protocol
Chukka says
Hello there,
I’m suffering from recurrent staphylococcus aureus infections like eye styles and also painful blisters on various parts of the body. Would this be one reason why my TPO antibodies are stuck at 998? I mean despite being on keto?
Also how do i eliminate it completely? Please suggest.
Dr. Izabella says
Chukka – thank you for reaching out. <3 There are many different potential root causes and triggers for Hashimoto's. Often, when a person has tried a number of interventions but still does not feel well, I find that they have some sort of underlying infection. Here are some articles you may find helpful:
VIRUSES
https://thyroidpharmacist.com/articles/viruses-may-trigger-hashimotos/
MOLD: A POTENTIAL TRIGGER OF HASHIMOTO’S
https://thyroidpharmacist.com/articles/mold-potential-trigger-hashimotos/
CANDIDA AND HASHIMOTO’S CONNECTION
https://thyroidpharmacist.com/articles/candida-and-hashimotos-connection/
Kerry says
Thank you for your great work towards helping people with Hashimotos! I’ve recently found Blastocystis hominis & Trophozoits of Endolimax nana via a stool sample. My GP has prescribed Flagyl or metronidazole for this. Is it best to test for Pylori, Yersinia, Borellia first and take all the prescribed antibiotics if needed at once or better to pace them out one at a time? Can natural alternatives really get rid of Endolimax and Blastocystis hominis? Many thanks for any advice you have : )
Dr. Izabella Wentz says
Kerry- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
Tam says
Dr. Izabella Wentz says
Tam- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
Micah says
I’ve been reading a lot on Hashimoto’s, diets, and also finding your root cause. When I did some notes following your dig-at-it exercise – I came to a conclusion that it must be my tonsils – could it be? I’ve had tons of problems with them as a kid (a lot of infections, antibiotics, etc) and now, me being an adult, they seem to have been infected for years but nothing has been done with them at any point (once I was told to rinse my throat with some herbs but it didn’t make any change).
What are your thoughts on this?
thanks a lot!
Izabella Wentz, PharmD says
Tara says
Dr. Izabella Wentz says
Tara- Did you know that if you live in the United States, the UK, Australia, Europe and most developed countries that add iodine to the salt supply and take thyroid medications, there’s a higher probability that you do have Hashimoto’s?
Depending on the source, estimates are that between 90-95% of those with hypothyroidism have Hashimoto’s.
But most doctors will never tell people that they have Hashimoto’s, or that their own immune system is attacking their thyroid. People are told that their “thyroid is sluggish”, and that these things happen with age and “Just take this pill, you’ll be fine.” I hope you check out these articles that I wrote.
ARE YOU DOING EVERYTHING FOR YOUR THYROID BUT NOT YET WELL?
https://thyroidpharmacist.com/articles/are-you-doing-everything-for-your-thyroid-but-not-yet-well/
DO YOU HAVE HYPOTHYROIDISM OR HASHIMOTO’S OR BOTH?
https://thyroidpharmacist.com/articles/do-you-have-hypothyroidism-or-hashimotos-or-both/
Here are the tests you need for diagnosis. Most endocrinologists don’t run them all so you will have to request them. Make sure to request a copy of your labs as well.
TOP 6 THYROID TESTS FOR DIAGNOSIS
https://thyroidpharmacist.com/articles/top-6-thyroid-tests/
Bonita says
Dr Anke Moeller says
Bonita says
Cindi says
Although, there’s been much improvement, I still need to address the bone loss and gums. Thank you so much. Your book was very helpful and I have recommended it to a few Hashi’s patients as well.
Izabella Wentz, PharmD says
Paula says
I’m awaiting results from my “GI effects complete stool test” (I was supplement-free for 3 days prior to test).
I take almost all of the supplements you recommend, including both VSL#3 and Betaine HCL with Pepsin.
But I’ve read somewhere that the HCL can lessen/negate the effects of the probiotics in general. Does the HCL negate the VSL#3 probiotics, or lessen their effects? When I was supplement-free I was surprised that my reflux did not return full-scale, so I’ve cut back on the Betaine HCL to 1x/day.
On a different matter, the VSL#3 pills get stuck in my esophagus frequently, despite drinking plenty of warm fluids, and even coconut oil to get it to pass through the esophagus. I wonder if that is a common complaint? Or, if it’s okay to open the capsule and drink the VSL#3 in water, etc.
Thanks for everything, your book is my ultimate Hashi guide, it’s well-highlighted, sticky-noted, and broken-in.
Paula says
Jane says
My question about infectious organisms relates to viruses that go dormant but never get cured, like herpes. Does this affect hashi’s and is there anything that can be done about it?
Dr. Izabella Wentz says
Jane- Thyroid tissue can regenerate, but the rate at which it does is not always predictable. Thus, some are able to stop the autoimmune attack on their thyroid and regain normal thyroid function. Others can reduce the dose of medications, and others will need to stay on the medications indefinitely. I’m currently working on some protocols to help with tissue regeneration.
Reversing Hashimoto’s means different things to different people. For some, it means a reduction in symptoms and for others it means a reduction in your antibodies. I had both. Here a few articles that might be helpful for you 🙂
IS IT POSSIBLE TO RECOVER THYROID FUNCTION IN HASHIMOTO’S
https://thyroidpharmacist.com/articles/is-it-possible-to-recover-thyroid-function-in-hashimotos
REVERSING AUTOIMMUNITY? AND THE PERFECT STORM
https://thyroidpharmacist.com/articles/reversing-autoimmunity-and-the-perfect-storm/
HASHIMOTO’S SELF CARE, GETTING AND STAYING IN REMISSION
https://thyroidpharmacist.com/articles/hashimotos-self-care
Carmelina Impellizzeri says
Dianne says
Paula says
I hope you don’t mind me adding my two cents, I can relate to the herpes virus issue, and here’s what I found: The article link (below) says that a daily L-lysine supplement can be taken to suppress herpes virus, although it doesn’t sound like the research is strong to support the claim, I take it because it’s not likely to be a detriment given my health conditions and it may help to suppress the virus. I’ve also read that there is no getting rid of it, only suppressing it. The article below also lists possible risks of taking L-lysine, but it provides some confusing recommendations about diet: https://umm.edu/health/medical/altmed/supplement/lysine
I’ve also read that it’s important to learn about the arginine-lysine ratio of foods: shouldn’t be too heavy on the arginine side (for example, nuts, chocolate, seeds have too much arginine). Here’s a list of the arginine-lysine content of foods, amongst many arginine-lysine ratio lists: http://www.sandiegohomeopathy.com/downloads/Lysine_Arginine_Foods.pdf
Another list about diet and herpes that seems very reasonable, and easier to follow, like an “eat more of this and less of that” approach is: http://www.herpes-coldsores.com/diet_and_nutrition_with_herpes.htm
But the bottom line seems to be to take L-lysine daily to tilt the daily scales of lysine and arginine contents in food in favor of lysine, and avoid, eat sparingly foods that are really high in arginine (chocolate, nuts, seeds, etc). The author of the first arginine-lysine ratio list above provided these recommendations for supplementing with L-lysine:
“How to take a Lysine supplement:
During flare-ups: Take 1000 mg three times a day with meals.
If you suffer from recurrent or frequent herpes outbreaks you can take a maintenance dose of 1000 mg of lysine per day
General Interactions with Lysine:
Do not take lysine with milk or dairy products. Very large doses of lysine can increase the toxicity of aminoglycoside antibiotics (i.e. gentamicin, neomycin and streptomycin).”
These are really good questions, and I’m so glad that you both were brave enough to ask, because I wasn’t brave enough.
I found a L-lysine product that I liked about 6 weeks ago, but I’m eager to know if Izabella even recommends L-lysine and/or other supplements/dietary tips for herpes suppression and also any research that supports a link between herpes and hashi.
Paula says
I hope you don’t mind me adding my two cents, I can relate to the herpes virus issue, and here’s what I found: The article link (below) says that a daily L-lysine supplement can be taken to suppress herpes virus, although it doesn’t sound like the research is strong to support the claim, I take it because it’s not likely to be a detriment given my health conditions and it may help to suppress the virus. I’ve also read that there is no getting rid of it, only suppressing it. The article below also lists possible risks of taking L-lysine, but it provides some confusing recommendations about diet: https://umm.edu/health/medical/altmed/supplement/lysine
I’ve also read that it’s important to learn about the arginine-lysine ratio of foods: shouldn’t be too heavy on the arginine side (for example, nuts, chocolate, seeds have too much arginine). Here’s a list of the arginine-lysine content of foods, amongst many arginine-lysine ratio lists: http://www.sandiegohomeopathy.com/downloads/Lysine_Arginine_Foods.pdf
Another list about diet and herpes that seems very reasonable, and easier to follow, like an “eat more of this and less of that” approach is: http://www.herpes-coldsores.com/diet_and_nutrition_with_herpes.htm
But the bottom line seems to be to take L-lysine daily to tilt the daily scales of lysine and arginine contents in food in favor of lysine, and avoid, eat sparingly foods that are really high in arginine (chocolate, nuts, seeds, etc). The author of the first arginine-lysine ratio list above provided these recommendations for supplementing with L-lysine:
“How to take a Lysine supplement:
During flare-ups: Take 1000 mg three times a day with meals.
If you suffer from recurrent or frequent herpes outbreaks you can take a maintenance dose of 1000 mg of lysine per day
General Interactions with Lysine:
Do not take lysine with milk or dairy products. Very large doses of lysine can increase the toxicity of aminoglycoside antibiotics (i.e. gentamicin, neomycin and streptomycin).”
These are really good questions, and I’m so glad that you both were brave enough to ask, because I wasn’t brave enough.
I found a L-lysine product that I liked about 6 weeks ago, but I’m eager to know if Izabella even recommends L-lysine and/or other supplements/dietary tips for herpes suppression and also any research that supports a link between herpes and hashi.
Cindi says
Izabella Wentz, PharmD says
Jeanna says
Dr. Izabella Wentz says
Jeanna- I personally struggled with pain in the form of body aches and stiffness as well as carpal tunnel in both arms in 2010, when I was first diagnosed with Hashimoto’s. It was awful, I had to wear braces on both arms all day and even at night for about 6 months.
I took NSAIDs every day to deal with the pain so I could get through my workday.
I hope these articles help you get started.
PAIN AND HASHIMOTOS
https://thyroidpharmacist.com/articles/pain-and-hashimotos
PAIN HASHIMOTOS AND FIBROMYALGIA…
https://thyroidpharmacist.com/articles/pain-hashimotos-and-fibromyalgia/
TURMERIC FOR YOUR THYROID AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/turmeric-for-your-thyroid-and-hashimotos
Hillary says
Also, if I’ve consumed pork and oysters, etc., over time and might have a Yersinia infection, is there a natural way to deal with that, as opposed to taking pharmaceutical antibiotics? I’ve had to take far too many of them in my life, and they’re likely a source of many of my problems already, so I’d really like to avoid taking any more. Thanks!
Dr. Izabella Wentz says
Hillary- Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
berni kellett says
Dr. Izabella Wentz says
Berni- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
Eric says
Dr. Izabella Wentz says
Eric- Without going into too much detail, the first of the crucial defining moments in my disease development may have started during my undergraduate studies at the University of Illinois. Due to the communal living setting of dormitories (and less than stellar hygiene habits of most college students) I had recurrent strep throat infections and even contracted mononucleosis, a viral infection caused by the Epstein-Barr Virus (EBV), which is implicated in triggering many autoimmune conditions. I received multiple courses of antibiotics as well as flu shots (which may be associated with EBV infections), and started birth control for menstrual cramps.
It is my belief that this combination had a profound impact on my gut flora, and thus my immune system.
Epstein-Barr is a virus that causes mononucleosis (commonly called “Mono”) , a debilitating viral infection that is common among college students, and is also known as the “kissing disease,” because individuals are exposed to the virus through saliva of those who are infected.
Specific immune cells known as CD8+ T cells are needed to fight off the Epstein-Barr virus, however, some individuals may have a low baseline level of these types of immune cells. (CD8+ T cells decrease with age, are lower in women, and in the presence of low vitamin D intake). When these fighter cells are low, the Epstein-Barr virus may take up residence in our organs (such as the thyroid) and essentially hijack the organ to help the virus hide and multiply.
The timing of infection may also matter as well, for example, children in developing countries usually contract the Epstein-Barr Virus when they are under the age of 10. This usually results in an asymptomatic infection—one that does not cause them symptoms. In contrast, in developed countries, where individuals are not usually exposed to the virus until they are in high school or college, the infection is symptomatic in 50% of the older kids affected. This is because by the time we reach college age, CD8+ T cells, the ones that fight EBV, have declined by threefold compared with the number of cells we had in childhood.
Additionally, animal fat and broths, soups and stews support the body’s ability to suppress the viruses. Monolaurin/lauric acid, one of the components of coconut oil, has been found to be active against the Epstein-Barr virus. Replication of many viruses including Epstein-Barr is inhibited by glycyrrhizic acid, an active component of licorice root. Quercetin, Co-Enzyme Q10, N-Acetylcysteine, and glutathione were also reported to be helpful in chronic fatigue syndrome because of their anti-viral properties.
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
Dee says
Dr. Izabella, I hope you are still checking this post. First, I would like to say, Thank You, for taking your time to research this and share it with others. God bless you abundantly. My question is about licorice and other supplements their estrogenic properties. On one of your article, you mentioned that hormones may be linked to autoimmune diseases. If that is one of the causes, would taking supplements like licorice or even garlic cause more problems? I was diagnosed with both Hashimoto’s and SLE. I have been busy reading your blog, and watching your video series. Although different diseases, both are autoimmune in nature and I am wondering if their root causes may have more in common thus the protocol could possibly be similar or the same. It may be wishful thinking on my part so that I can begin to implement one protocol instead of multiple protocols. I have one functional Doctor nearby. He is a Very nice man but not to keen on exploring much which is different than any of the doctors I watched in your videos. I’m sorry I got carried away and typed a lot more than I should have. I would love to hear your thoughts on estrogenic food and/or supplements if hormonal imbalance is one of the problems. I know you aren’t allowed to give medical advice but if it is allowed can you also share the length of time oil of oregano and berbere should be taken to eradicate bacteria, parasites, and candida? I read that you mentioned S. Boulardii should be taken twice a day for a minimum of 30 days but there was no information on the oil of oregano and the berbere.
Dr. Izabella Wentz says
Dee – thank you for following this page and for sharing. 🙂
I highly recommend that you work with a functional medicine clinician. It’s a whole medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms.
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
WHAT TYPE OF DOCTOR SHOULD YOU SEE IF YOU HAVE HASHIMOTO’S
https://thyroidpharmacist.com/articles/what-type-of-doctor-should-you-see-if-you-have-hashimotos
10 THINGS I WISH MY ENDOCRINOLOGIST WOULD HAVE TOLD ME
https://thyroidpharmacist.com/articles/10-things-i-wish-my-endocrinologist-would-have-told-me
CLINICIAN DATABASE
http://www.thyroidpharmacistconsulting.com/clinician-database.html
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://www.functionalmedicine.org/practitioner_search.aspx?id=117
me says
What do you recommend for those of us who don’t have access to a labs or a functional medicine physician? For example, I am low income. I am fortunate to have state-provided health insurance. I am fortunate to have a functional medicine physician I can go to. My functional medicine physician asked some questions, did some further tests, and then without even looking at the results of the further tests, tried to put me on Synthroid just like my doctor. I am leaving off a lot of story for the sake of brevity. I am moving soon, and I will be living somewhere where I don’t have access to any functional doctors or further testing. I am not alone in this position, especially since the start of covid. I’ve read your book (not recently, the library made me return it). I could probably buy a copy. But this is a general question about what people without access to labs and functional doctors should do? Because that is a LOT of people, especially with such a broken medical system. Thank you for your passion on this topic.
Dr. Izabella Wentz says
Hello, I’m so sorry you had this experience. I believe that everyone needs to find a practitioner that will let them be a part of the healthcare team. You want someone that can guide you, that will also listen to you and your concerns. You want someone that’s open to thinking outside of the box and who understands that you may not fit in with the standard of care. It’s a good idea to ask some standard questions when contacting a new doctor for the first time. Something else to consider is you can work with a functional doctor remotely, via Zoom or another platform. You could also contact your local pharmacist or compounding pharmacy, who may be able to point you to a local doctor who has a natural functional approach. But I encourage you to keep looking for the right one for you! When it comes to testing you may wan to consider self ordering as well. Here are some resources you might find helpful.
CLINICIAN DATABASE
https://thyroidpharmacist.com/database-recommended-clinicians/
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://ifm.org/find-a-practitioner/
COMPOUNDING PHARMACIES
https://thyroidpharmacist.com/database-recommended-compounding-pharmacies/
Wendy Bolt says
Dr. Izabella Wentz says
Wendy- Here are a couple of articles you may find interesting! 🙂
INFECTIONS AS HIDDEN TRIGGERS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/infections-as-hidden-triggers-for-hashimotos
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes
jennie says
ear infection of middle ear
Dr. Izabella Wentz says
jennie- Here are a couple of articles you may find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes
INFECTIONS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/infections-and-hashimotos/
pankaj says
Dr. Izabella Wentz says
Pankaj- Thyroid tissue can regenerate, but the rate at which it does is not always predictable. Thus, some are able to stop the autoimmune attack on their thyroid and regain normal thyroid function. Others can reduce the dose of medications, and others will need to stay on the medications indefinitely. I’m currently working on some protocols to help with tissue regeneration.
Reversing Hashimoto’s means different things to different people. For some, it means a reduction in symptoms and for others it means a reduction in your antibodies. I had both. Here a few articles that might be helpful for you 🙂
IS IT POSSIBLE TO RECOVER THYROID FUNCTION IN HASHIMOTO’S
https://thyroidpharmacist.com/articles/is-it-possible-to-recover-thyroid-function-in-hashimotos
REVERSING AUTOIMMUNITY? AND THE PERFECT STORM
https://thyroidpharmacist.com/articles/reversing-autoimmunity-and-the-perfect-storm/
HASHIMOTO’S SELF CARE, GETTING AND STAYING IN REMISSION
https://thyroidpharmacist.com/articles/hashimotos-self-care
Marianne says
You mention Thytrophin PMG supplement to be used as a decoy to attract attacking white blood cells and antibodies. What if, as in my case one has reoccurring EBV infections and antibodies for H. Pylori? If either of these were the triggers for the thyroiditis, would Thytrophin PMG draw the white blood cells away from the infectious agents or does it help clear the way for the white blood cells and antibodies to attack only the infectious agents and not the thyroid cells?
I guess the short question is, is it safe to use Thytrophin PMG if you suspect the trigger for your Hashimoto’s Disease to be infectious agents?
Thank you so much
Dr. Izabella Wentz says
Marianne- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
An says
Dr. Izabella Wentz says
An- Did you know that if you live in the United States, the UK, Australia, Europe and most developed countries that add iodine to the salt supply and take thyroid medications, there’s a higher probability that you do have Hashimoto’s?
Depending on the source, estimates are that between 90-95% of those with hypothyroidism have Hashimoto’s.
But most doctors will never tell people that they have Hashimoto’s, or that their own immune system is attacking their thyroid. People are told that their “thyroid is sluggish”, and that these things happen with age and “Just take this pill, you’ll be fine.” I hope you check out these articles that I wrote.
ARE YOU DOING EVERYTHING FOR YOUR THYROID BUT NOT YET WELL?
https://thyroidpharmacist.com/articles/are-you-doing-everything-for-your-thyroid-but-not-yet-well/
DO YOU HAVE HYPOTHYROIDISM OR HASHIMOTO’S OR BOTH?
https://thyroidpharmacist.com/articles/do-you-have-hypothyroidism-or-hashimotos-or-both/
Here are the tests you need for diagnosis. Most endocrinologists don’t run them all so you will have to request them. Make sure to request a copy of your labs as well.
TOP 6 THYROID TESTS FOR DIAGNOSIS
https://thyroidpharmacist.com/articles/top-6-thyroid-tests/
Rachelle says
I’m assuming, based on this comment (please confirm) that eliminating iodine from the diet is what you’d suggest? I hear people claiming that high doses of iodine (Lugol’s) is important to support the thyroid; however, if I even eat small amounts of kelp powder, it makes my thyroid swell (I can feel the discomfort in my throat) and causes major mood swings. What is going on with so many people suggesting supplementing with this?
Dr. Izabella Wentz says
Rachelle- I’m very hesitant in recommending iodine in Hashimoto’s. Although iodine serves as fuel for our thyroid and is very important in iodine deficiency hypothyroidism, Hashimoto’s is a different mechanism. It’s like pouring gas into an engine that’s on fire… that’s essentially what’s happening in Hashi’s, thyroid inflammation, and adding iodine to the mix before putting out the fire and fixing the engine may result in further damage to the thyroid. In those with a predisposition to autoimmunity, this has been documented time and time again, animal and human studies. I have spent 4 years researching this and have seen too many people suffering the consequences of adding iodine too soon. My approach is, let’s fix the engine first (usually a gut issue), and then add the fuel once we know that the engine is no longer on fire. Hope that you will check out my book. I have a whole chapter on the iodine controversy that references numerous studies as well as the work of Abraham and Brownstein.
AMAZON
Hashimoto’s Root Cause
http://www.amazon.com/gp/product/0615825796?ie=UTF8&camp=1789&creativeASIN=0615825796&linkCode=xm2&tag=thyroipharma-20
Hashimoto’s Protocol
https://smile.amazon.com/Hashimotos-Protocol-Reversing-Thyroid-Symptoms/dp/006257129X/ref=sr_1_1?ie=UTF8&qid=1482698453&sr=8-1&keywords=Hashimoto%27s+Protocol
susan says
Dr. Izabella Wentz says
Susan- Here is an article you may find interesting! 🙂
CANDIDA AND HASHIMOTOS CONNECTION
https://thyroidpharmacist.com/articles/candida-and-hashimotos-connection
Cari-Lynn says
Dr. Izabella Wentz says
Cari-Lynn- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
Hyrije Kastrati says
Dr. Izabella Wentz says
Hyrije- Graves and Hashimoto’s are both autoimmune conditions that affect the thyroid. They are thought to be closely related. Sometimes one turns into the other. The difference is the site of the antibody attack. In Hashimoto’s, the antibodies are found to thyroglobulin (in 80%) and thyroid peroxidase (TPO) enzyme (in 95% of people)-Hashimoto’s results in hypothyroidism and is usually treated with Synthroid and replacement hormone.
The same antibodies may be present in a smaller percentage of people who have Graves, but the main antibody is to the TSH Receptor (TSHR-Ab). Usually people with Graves have hyperthyroidism and they are treated conventionally with thyroid suppressing drugs (methimazole) or radioactive iodine to destroy the thyroid. At that point, the thyroid will no longer produce hormones on its own and these people end up on Synthroid as well.
Most thyroid conditions result from the immune system attacking the thyroid because the immune system is out of balance. Even when the thyroid is taken out surgically or treated with radioactive iodine the autoimmunity still persists in most cases. Many people will have their thyroids removed, and will develop new autoimmune disorders such as Lupus, Rheumatoid arthritis, etc. The immune system just finds a different target. We need to rebalance the immune system to prevent this (sometimes the autoimmunity can be reversed as well! The gut determines your immune system. With the exception of discussing proper thyroid medication dosing, the majority of my website and my book focuses on balancing the immune system. The info I present is based on my own research in journey for overcoming my autoimmune thyroid condition.
http://www.amazon.com/gp/product/0615825796?ie=UTF8&camp=1789&creativeASIN=0615825796&linkCode=xm2&tag=thyroipharma-20
Rose says
Dr. Izabella Wentz says
Rose- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
carolyn sauers says
I am allerg to most of antibiotics. I am on oregano oil, cat claw (TOA-free) carnivora,Teasel. My doc said not to “worry” about my TPO number. She thinks I have Lymes and candida. So far all this treatment as got me is a tummy ache. Any in put would be of much help.
Carolyn
Dr. Izabella Wentz says
Carolyn- Here are two articles you may find interesting!
LYME AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/lyme-and-hashimotos
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
CANDIDA AND HASHIMOTOS CONNECTION
https://thyroidpharmacist.com/articles/candida-and-hashimotos-connection
patty says
Dr. Izabella Wentz says
Patty- Without going into too much detail, the first of the crucial defining moments in my disease development may have started during my undergraduate studies at the University of Illinois. Due to the communal living setting of dormitories (and less than stellar hygiene habits of most college students) I had recurrent strep throat infections and even contracted mononucleosis, a viral infection caused by the Epstein-Barr Virus (EBV), which is implicated in triggering many autoimmune conditions. I received multiple courses of antibiotics as well as flu shots (which may be associated with EBV infections), and started birth control for menstrual cramps.
It is my belief that this combination had a profound impact on my gut flora, and thus my immune system.
Epstein-Barr is a virus that causes mononucleosis (commonly called “Mono”) , a debilitating viral infection that is common among college students, and is also known as the “kissing disease,” because individuals are exposed to the virus through saliva of those who are infected.
Specific immune cells known as CD8+ T cells are needed to fight off the Epstein-Barr virus, however, some individuals may have a low baseline level of these types of immune cells. (CD8+ T cells decrease with age, are lower in women, and in the presence of low vitamin D intake). When these fighter cells are low, the Epstein-Barr virus may take up residence in our organs (such as the thyroid) and essentially hijack the organ to help the virus hide and multiply.
The timing of infection may also matter as well, for example, children in developing countries usually contract the Epstein-Barr Virus when they are under the age of 10. This usually results in an asymptomatic infection—one that does not cause them symptoms. In contrast, in developed countries, where individuals are not usually exposed to the virus until they are in high school or college, the infection is symptomatic in 50% of the older kids affected. This is because by the time we reach college age, CD8+ T cells, the ones that fight EBV, have declined by threefold compared with the number of cells we had in childhood.
Additionally, animal fat and broths, soups and stews support the body’s ability to suppress the viruses. Monolaurin/lauric acid, one of the components of coconut oil, has been found to be active against the Epstein-Barr virus. Replication of many viruses including Epstein-Barr is inhibited by glycyrrhizic acid, an active component of licorice root. Quercetin, Co-Enzyme Q10, N-Acetylcysteine, and glutathione were also reported to be helpful in chronic fatigue syndrome because of their anti-viral properties.
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
Lila says
I was diagnosed with Hashimoto’s thyroiditis in 2008 and in the same year I contracted parasites from bad water namely Blastocystis species and Dientamoeba species. I am wondering if the molecular mimicry theory can be applied to these organisms as well. Could these parasites have triggered the antibodies to attack my thyroid?
Dr. Izabella Wentz says
Lila- Here is some information you may find interesting.
Three things MUST be present in order for autoimmunity to occur…
1. Genetic predisposition
2. Environmental triggers
3. Intestinal permeability (leaky gut)
Developing autoimmunity is like a three-legged stool, all of these factors must be present for autoimmunity to occur! When you remove one of these, you can prevent or stop autoimmune disease. While we can’t change genes, if we know the trigger, we can remove it and we can heal the gut.
REVERSING AUTOIMMUNITY AND THE PERFECT STORM
https://thyroidpharmacist.com/articles/reversing-autoimmunity-and-the-perfect-storm/
IS HASHIMOTO’S HYPOTHYROIDISM GENETIC
https://thyroidpharmacist.com/articles/is-hashimotos-genetic
Jennifer says
I cleared up the Lupus taking wheat out of my diet, also took out dairy but the Fibromyalgia I was diagnosed with has never changed. I have sore throats, chronic muscle and joint pain and fatigue that never goes away.
The infections makes more sense. This all started with infections, one after another after a fall at work. Throat infections, kidney infections, lung infections, gut aches, throwing up blood and severe bloody diarrhea. It was like I had a virus that kept going through my organs and has never went away to this day.
I am looking for a permanent solution. Because candida, pylori, herpes virus and others hide in the lining of the gut, we have to kill them off when active. We then need to fire up our immune system with certain herbs and the right food so we can heal our microbiome to keep invaders in check.
I read that candida hides deep and there is a way to bring them out and cut their heads off with some bone something (didn’t really understand what she said), then cleanse and rebuild. The trick is to kill them off when they are active.
I believe sugar feeds them and I have had a sugar addiction most of my life. Interesting to find out about the arginine-lysine foods as I eat a lot of nuts and seeds and used to eat a lot of chocolate.
I am not sure where to get the test for the virus and bacteria’s in Canada though. Great info, thanks for sharing ladies.
Dr. Izabella Wentz says
Jennifer- Here is an article you may find interesting!:)
CANDIDA AND HASHIMOTOS CONNECTION
https://thyroidpharmacist.com/articles/candida-and-hashimotos-connection
Debbie Brown says
Dr. Izabella Wentz says
Debbie- Here is some information you may find interesting.
Three things MUST be present in order for autoimmunity to occur…
1. Genetic predisposition
2. Environmental triggers
3. Intestinal permeability (leaky gut)
Developing autoimmunity is like a three-legged stool, all of these factors must be present for autoimmunity to occur! When you remove one of these, you can prevent or stop autoimmune disease. While we can’t change genes, if we know the trigger, we can remove it and we can heal the gut.
REVERSING AUTOIMMUNITY AND THE PERFECT STORM
https://thyroidpharmacist.com/articles/reversing-autoimmunity-and-the-perfect-storm/
IS HASHIMOTO’S HYPOTHYROIDISM GENETIC
https://thyroidpharmacist.com/articles/is-hashimotos-genetic
Mary Kay says
Dr. Izabella Wentz says
Mary- Without going into too much detail, the first of the crucial defining moments in my disease development may have started during my undergraduate studies at the University of Illinois. Due to the communal living setting of dormitories (and less than stellar hygiene habits of most college students) I had recurrent strep throat infections and even contracted mononucleosis, a viral infection caused by the Epstein-Barr Virus (EBV), which is implicated in triggering many autoimmune conditions. I received multiple courses of antibiotics as well as flu shots (which may be associated with EBV infections), and started birth control for menstrual cramps.
It is my belief that this combination had a profound impact on my gut flora, and thus my immune system.
Epstein-Barr is a virus that causes mononucleosis (commonly called “Mono”) , a debilitating viral infection that is common among college students, and is also known as the “kissing disease,” because individuals are exposed to the virus through saliva of those who are infected.
Specific immune cells known as CD8+ T cells are needed to fight off the Epstein-Barr virus, however, some individuals may have a low baseline level of these types of immune cells. (CD8+ T cells decrease with age, are lower in women, and in the presence of low vitamin D intake). When these fighter cells are low, the Epstein-Barr virus may take up residence in our organs (such as the thyroid) and essentially hijack the organ to help the virus hide and multiply.
The timing of infection may also matter as well, for example, children in developing countries usually contract the Epstein-Barr Virus when they are under the age of 10. This usually results in an asymptomatic infection—one that does not cause them symptoms. In contrast, in developed countries, where individuals are not usually exposed to the virus until they are in high school or college, the infection is symptomatic in 50% of the older kids affected. This is because by the time we reach college age, CD8+ T cells, the ones that fight EBV, have declined by threefold compared with the number of cells we had in childhood.
Additionally, animal fat and broths, soups and stews support the body’s ability to suppress the viruses. Monolaurin/lauric acid, one of the components of coconut oil, has been found to be active against the Epstein-Barr virus. Replication of many viruses including Epstein-Barr is inhibited by glycyrrhizic acid, an active component of licorice root. Quercetin, Co-Enzyme Q10, N-Acetylcysteine, and glutathione were also reported to be helpful in chronic fatigue syndrome because of their anti-viral properties.
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
anne marie says
Dr. Izabella Wentz says
Anne- Without going into too much detail, the first of the crucial defining moments in my disease development may have started during my undergraduate studies at the University of Illinois. Due to the communal living setting of dormitories (and less than stellar hygiene habits of most college students) I had recurrent strep throat infections and even contracted mononucleosis, a viral infection caused by the Epstein-Barr Virus (EBV), which is implicated in triggering many autoimmune conditions. I received multiple courses of antibiotics as well as flu shots (which may be associated with EBV infections), and started birth control for menstrual cramps.
It is my belief that this combination had a profound impact on my gut flora, and thus my immune system.
Epstein-Barr is a virus that causes mononucleosis (commonly called “Mono”) , a debilitating viral infection that is common among college students, and is also known as the “kissing disease,” because individuals are exposed to the virus through saliva of those who are infected.
Specific immune cells known as CD8+ T cells are needed to fight off the Epstein-Barr virus, however, some individuals may have a low baseline level of these types of immune cells. (CD8+ T cells decrease with age, are lower in women, and in the presence of low vitamin D intake). When these fighter cells are low, the Epstein-Barr virus may take up residence in our organs (such as the thyroid) and essentially hijack the organ to help the virus hide and multiply.
The timing of infection may also matter as well, for example, children in developing countries usually contract the Epstein-Barr Virus when they are under the age of 10. This usually results in an asymptomatic infection—one that does not cause them symptoms. In contrast, in developed countries, where individuals are not usually exposed to the virus until they are in high school or college, the infection is symptomatic in 50% of the older kids affected. This is because by the time we reach college age, CD8+ T cells, the ones that fight EBV, have declined by threefold compared with the number of cells we had in childhood.
Additionally, animal fat and broths, soups and stews support the body’s ability to suppress the viruses. Monolaurin/lauric acid, one of the components of coconut oil, has been found to be active against the Epstein-Barr virus. Replication of many viruses including Epstein-Barr is inhibited by glycyrrhizic acid, an active component of licorice root. Quercetin, Co-Enzyme Q10, N-Acetylcysteine, and glutathione were also reported to be helpful in chronic fatigue syndrome because of their anti-viral properties.
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
Angie says
Dr. Izabella Wentz says
Angie- When it comes to weight gain these are a couple of things to think about.
1) What was your recent TSH, Free T3 and Free T4? Sometimes when those numbers are on the outskirts of normal, your metabolic rate may still be impaired making it more difficult for you to burn calories. Most people report feeling well with a TSH between 0.5-2.
2) What type of medication are you on? Some report more weight loss with T4/T3 combinations (Armour, Nature-Throid, compounded medications) versus T4 medications (Synthroid, Levoxyl, Tirosint) alone. T4 is a precursor to T3, but some individuals do not convert T4 to T3 properly, and the T3 component is the metabolically active one.
3) What type of diet are you eating? Some report more weight loss with T4/T3 combination vs T4 alone. Some do not convert T4 properly.The Standard American Diet (S.A.D.) full of sugar and simple carbohydrates is perfectly designed to cause us to gain weight year after year. Even yogurts that are marketed as “healthy” contain the equivalent of 16 teaspoons of sugar. Divorcing the S.A.D. is often a step that many of us must take to not just lose weight, but to also feel better. Some diets that have been helpful include the Body Ecology Diet, the Paleo Diet, the Virgin Diet, Autoimmune Paleo Diet, GAPS diet, SCD diet, Weston A. Price Diet, or the Mediterranean Diet. You may need to modify these diets to your own individuality.
BEST DIET FOR HASHIMOTO’S AND HYPOTHYROIDISM
https://thyroidpharmacist.com/articles/best-diet-for-hashimotos-hypothyroidism
HOW TO LOSE WEIGHT WITH HASHIMOTO’S AND HYPOTHYROIDISM
https://thyroidpharmacist.com/articles/how-to-lose-weight-with-hashimotos
elle t says
Result: <0.4. It says it's in normal range but it was not negative. Do I still implement H.P. protocol? Thank you,
Dr. Izabella Wentz says
Elle- Work with your doctor to test for infections, and use antibiotics judiciously, as they can be incredibly dangerous when used incorrectly and lead to multi-drug resistance, an elimination of the beneficial bacterial flora and numerous side effects. There is a multitude of different antibiotics, each with a different group of bacteria they target, and each with their own set of side effects. Blindly taking antibiotics without knowing the cause of your infection may end up inadvertently destroying the beneficial bacteria while letting pathogenic and opportunistic bacteria thrive.
Be sure to supplement with probiotics during courses of antibiotic therapy, but at different times throughout the day so that the beneficial bacteria in the probiotics are not killed by the antibiotics. Work with your pharmacist to find out the half-life of your antibiotics and to find an optimal time to take probiotics.
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
Rachel says
Does licorice candy get rid of H. Pylori? As far as probiotics, will eating yogurt every day help?
Dr. Izabella Wentz says
Rachel- Here is an article you may find interesting! 🙂
THE FOUR BEST PROBIOTICS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-four-best-probiotics-for-hashimotos
Shakira says
I read your articles because I have hypothyroidism and so does my husband. He has hashimotos though and so does my mother in law. I have rheumatoid arthritis which you know is also an autoimmune disorder so this article has re-inspired me to keep searching for the cause of my RA. In 2012-2013 I was working a nursing job that was killing me! I was run down, an insomniac and continued to ignore my health because I thought I would just bounce back. Oh how I was so very wrong!! I had pneumonia, bronchitis and sinus infections multiple times and kept bugging my dr to look further into my poor health. Looking back now, I wonder what damage I did to my body and what all these infections and rounds of antibiotics did to me!! I also suffered from gerd and was on a proton pump inhibitor for years at that point. I was gaining weight rapidly and couldn’t figure out why as I had tried to eat healthier and had always been a skinny person who could eat anything. My life is drastically different now for the better in that I stopped smoking and socially drinking, I exercise and eat clean (paleo, gluten free, organic) and I am slowly trying to get my life back. My RA and fibromyalgia are tuff obstacles though so any advice, tips etc would be greatly appreciated!!
Thanks!!
Shakira
Dr. Izabella Wentz says
I am so happy to hear you are feeling better!! I think it is amazing that you have empowered yourself to take your health back! I look forward to hearing more of your progress on this page! You may be interested in checking out the Root Cause Recipe Portal. It is full of autoimmune paleo and paleo recipes. You’re able to organize weekly shopping lists, meal planning, etc. Hope you check it out. 🙂
http://rootcauserecipes.com/
Anita says
Hi all! I have had recurrent EBV infection with VERY HIGH titers. Diagnosed with Hyperthyroid 30+yrs ago, off and on Methimazole since, diagnosed with Fibromyalgia, Myofascial Pain syndrome and Chronic Fatigue 15 yrs ago. Interesting thing is that I lived in East Africa in my teen years in the 60’s and had numerous parasitic illnesses. Really starting to wonder how all this is tied together. Have suffered with IBS since before it was called that which started with amoebic dysentery at 15. My RA levels and gluten tolerance levels are low. Had a horrible time with Mono in early twenties and some sort of oral herpes infection as an adolescent, I only remember that it hurt to drink water! I have had too many other diagnoses to list here. Would appreciate any and all recommendations, thank you!
Dr. Izabella Wentz says
Without going into too much detail, the first of the crucial defining moments in my disease development may have started during my undergraduate studies at the University of Illinois. Due to the communal living setting of dormitories (and less than stellar hygiene habits of most college students) I had recurrent strep throat infections and even contracted mononucleosis, a viral infection caused by the Epstein-Barr Virus (EBV), which is implicated in triggering many autoimmune conditions. I received multiple courses of antibiotics as well as flu shots (which may be associated with EBV infections), and started birth control for menstrual cramps.
It is my belief that this combination had a profound impact on my gut flora, and thus my immune system.
Epstein-Barr is a virus that causes mononucleosis (commonly called “Mono”) , a debilitating viral infection that is common among college students, and is also known as the “kissing disease,” because individuals are exposed to the virus through saliva of those who are infected.
Specific immune cells known as CD8+ T cells are needed to fight off the Epstein-Barr virus, however, some individuals may have a low baseline level of these types of immune cells. (CD8+ T cells decrease with age, are lower in women, and in the presence of low vitamin D intake). When these fighter cells are low, the Epstein-Barr virus may take up residence in our organs (such as the thyroid) and essentially hijack the organ to help the virus hide and multiply.
The timing of infection may also matter as well, for example, children in developing countries usually contract the Epstein-Barr Virus when they are under the age of 10. This usually results in an asymptomatic infection—one that does not cause them symptoms. In contrast, in developed countries, where individuals are not usually exposed to the virus until they are in high school or college, the infection is symptomatic in 50% of the older kids affected. This is because by the time we reach college age, CD8+ T cells, the ones that fight EBV, have declined by threefold compared with the number of cells we had in childhood.
Additionally, animal fat and broths, soups and stews support the body’s ability to suppress the viruses. Monolaurin/lauric acid, one of the components of coconut oil, has been found to be active against the Epstein-Barr virus. Replication of many viruses including Epstein-Barr is inhibited by glycyrrhizic acid, an active component of licorice root. Quercetin, Co-Enzyme Q10, N-Acetylcysteine, and glutathione were also reported to be helpful in chronic fatigue syndrome because of their anti-viral properties. Here are a couple of articles you may find helpful!!
THE COMMON ROOT CAUSE OF HASHIMOTO’S, HIVES AND IBS
https://thyroidpharmacist.com/articles/the-common-root-cause-of-hashimotos-hives-and-ibs
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
Molly says
Wow Izabella our stories have a LOT of similarities! I’m wondering if you have or know of a list of pathogens besides the 3 listed (h pylori, Lyme, yersinia) that are known or suspected to cause the same molecular mimicry of the thyroid? Stool tests for h pylori and yersinia are negative and Lyme is so controversial…I’ve treated it for years with “LLMDs” but believe I really don’t have it, as I have never improved with Lyme tx (and certain infections cause cross reaction). Stool tests show I have a high amount of klebsiella species, and I’ve found conflicting and variable info about it with some sources saying it’s commensal and others saying it’s pathogenic. Any thoughts?
Dr. Izabella Wentz says
Molly – I am unable to give out any direct personal medical advice here on this page. I highly recommend that you work with a functional medicine clinician. It’s a whole medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms.
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
CLINICIAN DATABASE
http://www.thyroidpharmacistconsulting.com/clinician-database.html
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://www.functionalmedicine.org/practitioner_search.aspx?id=117
Stacy Lundblad says
Have you ever worked with anyone wiwth Hasis and Burning Mouth that feels like poison is coming right out of your mouth! Infrared Hot House has helped but also seems to be pulling out toxins. What could this be? I am working with a funtional chiro who understands my MTHFR issues and is doing neuropathy therapy.
Please let me know what you might think that this is. All silver fillings out recently but might still be in tissues. Have EBV and Herpies Simplex 1 and working on the gut for years!
Dr. Izabella Wentz says
Stacy – thank you for following this page. 🙂
Please, understand that due to liability issues, I am unable to answer specific medical questions.
You may be interested in these articles.
MTHFR
https://thyroidpharmacist.com/articles/mthfr-hashimotos-and-nutrients
INFECTIONS AS HIDDEN TRIGGERS FOR HASHIMOTO’S
https://thyroidpharmacist.com/articles/infections-as-hidden-triggers-for-hashimotos
Caroline says
I’ve had a goiter that fluctuates in size-pretty much since I was a toddler. I also had hypothyroid symptoms growing up and was finally put on synthroid in my early 20s. It didn’t work.
I went gluten free at 25, then full paleo at 27. I tried armor and other ‘thyroid supplements’ during this time. Nothing was working. My blood work was and still is normal yet my goiter is still here. I did the iodine protocol for almost two years-great results but goiter size never changed.
I’m at a loss and feeling totally hopeless.
Dr. Izabella Wentz says
Caroline – thank you so much for following this page.
Did you know that if you live in the United States, Australia, Europe and most developed countries that add iodine to the salt supply and take thyroid medications, there’s a higher probability that you do have Hashimoto’s?
Depending on the source, estimates are that between 90-95% of those with hypothyroidism have Hashimoto’s.
But most doctors will never tell people that they have Hashimoto’s, or that their own immune system is attacking their thyroid. People are told that their “thyroid is sluggish”, and that these things happen with age and “Just take this pill, you’ll be fine.” I hope you check out these articles that I wrote.
ARE YOU DOING EVERYTHING FOR YOUR THYROID BUT NOT YET WELL?
https://thyroidpharmacist.com/articles/are-you-doing-everything-for-your-thyroid-but-not-yet-well/
DO YOU HAVE HYPOTHYROIDISM OR HASHIMOTO’S OR BOTH?
https://thyroidpharmacist.com/articles/do-you-have-hypothyroidism-or-hashimotos-or-both/
Here are the tests you need for diagnosis. Most endocrinologists don’t run them all so you will have to request them. Make sure to request a copy of your labs as well.
TOP 6 THYROID TESTS FOR DIAGNOSIS
https://thyroidpharmacist.com/articles/top-6-thyroid-tests/
Kahu says
Hi there, I keep reading that by far the most common type of hypothyroidism is hashing toss&, so what about plain old non autoimmune hypothyroidism? I have what I highly suspect is leaky gut, and possibly other autoimmune conditions but just hypothyroidism. Also your series seemed to focus on hashis but that might have only been the parts I saw. Any thoughts on standard hypothyroidism? Thank you!
Dr. Izabella Wentz says
Kahu – thank you so much for following this page.
Did you know that if you live in the United States, Australia, Europe and most developed countries that add iodine to the salt supply and take thyroid medications, there’s a higher probability that you do have Hashimoto’s?
Depending on the source, estimates are that between 90-95% of those with hypothyroidism have Hashimoto’s.
But most doctors will never tell people that they have Hashimoto’s, or that their own immune system is attacking their thyroid. People are told that their “thyroid is sluggish”, and that these things happen with age and “Just take this pill, you’ll be fine.” I hope you check out these articles that I wrote.
ARE YOU DOING EVERYTHING FOR YOUR THYROID BUT NOT YET WELL?
https://thyroidpharmacist.com/articles/are-you-doing-everything-for-your-thyroid-but-not-yet-well/
DO YOU HAVE HYPOTHYROIDISM OR HASHIMOTO’S OR BOTH?
https://thyroidpharmacist.com/articles/do-you-have-hypothyroidism-or-hashimotos-or-both/
Here are the tests you need for diagnosis. Most endocrinologists don’t run them all so you will have to request them. Make sure to request a copy of your labs as well.
TOP 6 THYROID TESTS FOR DIAGNOSIS
https://thyroidpharmacist.com/articles/top-6-thyroid-tests/
Kerri says
If I had gut infections or other infections, wouldn’t it show up on blood work? CBC with differential?
Also what could it mean if alkaline phosphatase was high instead of low?
Dr. Izabella Wentz says
Kerri – thank you for following this page. Please, understand that due to liability issues, I am unable to answer specific medical questions.
I highly recommend that you work with a functional medicine clinician. It’s a whole medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms.
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
WHAT TYPE OF DOCTOR SHOULD YOU SEE IF YOU HAVE HASHIMOTO’S
https://thyroidpharmacist.com/articles/what-type-of-doctor-should-you-see-if-you-have-hashimotos
10 THINGS I WISH MY ENDOCRINOLOGIST WOULD HAVE TOLD ME
https://thyroidpharmacist.com/articles/10-things-i-wish-my-endocrinologist-would-have-told-me
CLINICIAN DATABASE
http://www.thyroidpharmacistconsulting.com/clinician-database.html
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://www.functionalmedicine.org/practitioner_search.aspx?id=117
Carrie says
Hi Dr Izabella
Thank you so much for your website and all the information you provide and the queries you take time to answer. I’m about to buy your books. I’ve only recently been diagnosed with Hashimotos (I basically had to tell my doctor and get her to get a second opinion when I noticed my anti TG was high on a blood test from over a year ago and nobody had picked this up. Anti TPO normal) and i have had some bad experiences over the years with doctors and endocrinologists in France where I live since being diagnosed hypothyroid in 2009.
I’ve found a nutritionist and functional médecine practitioner but we haven’t got started yet as she is away for a couple of months. I’m kind of going it alone right now and it is such a minefield. Every time I read something and decide to explore that line of treatment I seem to then read something conflicting. I am taking many of the supplements you recommend and have begun to feel quite a bit better but was still suffering a lot of gut problems. I read about oregano oil and decided to try that but almost immediately suffered symptoms of candida die off. I’ve been aware for a few years that I have a candida problem that needs to be addressed and this seemed like a convenient effect along with trying to rebalance my gut flora. Thankfully the die off symptoms are subsiding after a few days. I know you’re supposed to stop as this is a sign that your body is struggling with the toxicity of the dying candida but I was worried that stopping would encourage whatever else is wrong in my gut. But I’m flying blind aren’t I? i seem to be obsessively trying to take anything and everything I can get my hands on and that makes sense to help my situation but I am now confused. Is oregano oil killing everything in my gut and therefore a bad thing? I started taking Align today but I don’t know if that is pointless because the oregano oil will kill the b. infantis 35624 and having just read several more of your articles and posts I don’t even know whether that is the strain I should be taking!
I’ve taken one so far as only received it today and had a churning stomach and gas ever since. But that could be down to eating cheese! I have cut down but not eliminated dairy. Maybe I am trying to do all of this too fast, I am impatient and fed up of being so unwell. I am now strictly gluten free but it’s not solving all the problems at all. Maybe I need to calm down, read your books and stop spending money on supplements left, right and centre, so that I can formulate a better plan. I don’t trust anyone to help me here. French medicine seems not to take any notice of the gut and the endo I’ve seen is worse than useless. I don’t know what the point in one will be for me now so don’t even want to try another though I’ve been referred. I went my own way and started taking Thiroyd three months ago because nobody would listen to me or let me have T3 and you can’t get NDT in France, it’s illegal!!!
Sorry, this comment devolved from a simple question about whether to take Align whilst treating with oregano oil or wait till after.
If any body is “listening” thank you. Any advice welcome.
Dr. Izabella Wentz says
Carrie – thank you for following this page. Not everyone will need every single supplement! In fact, I believe that most nutrients should come from the diet. This is why I always list food sources in the book and on the blog, for most of the nutrients, vitamins, minerals and probiotics that are depleted in Hashimoto’s. However, some may require/prefer supplements and the supplements on the website are a resource for those that do. I recommend getting tested for deficiencies to determine your need for a supplement as instructed in the book and blog. I also don’t recommend starting multiple supplements all at once. I recommend starting one at a time, and then adding another a week or so later once it has been confirmed that the first supplement is not causing any harm.
I do have a full supplements chapter in my book. Have you checked it out? Not everyone should be taking every supplement and the book will help uncover your root cause. This will help you figure out your supplementation.
Hashimoto’s Root Cause
http://www.amazon.com/gp/product/0615825796?ie=UTF8&camp=1789&creativeASIN=0615825796&linkCode=xm2&tag=thyroipharma-20
Hashimoto’s Protocol
thyroidpharmacist.com/protocol
Manh says
Hello Dr Izabella,
I’m currently reading your book and while I understand the idea behind taking Thytrophin PMG, it raises 2 questions for me.
-Is it possible that it would cause inflammation in the gut and/or impact digestion as the food that is being digested is being simultaneously attacked?
-Since this pill contains thyroid DNA, would it prompt the body to increase its supply of antibodies?
Dr. Izabella says
Manh – thank you for following this page. For questions pertaining to the protocols please contact my team at program@thyroidpharmacist.com and they will be happy to help you.
Kirsten P says
It has been difficult to find a lab service in rural Canada such as the one you recommend for a comprehensive stool sample. Have you any recommendations?
Dr. Izabella says
Kirsten – thank you for following this page. Please contact my team at info@thyroidpharmacist.com and they will be happy to help you.
Jeannie says
Hi Dr. Wentz, thank you for giving me hope. I’ve been in a hashimoto flare since diagnosed in 2016. Seems I’ve gotten worse lately, extremely tired, joint pain you name it. 2 weeks ago I was diagnosed with a UTI, normal should be between 2-5 my WBC was 29. It was retested and now WBC is 13 so now on a round of cipro for 5 days. I didn’t have the normal burning and pain that normally comes with a UTI. Who knows how long I’ve had this. I am praying and hoping that once this is gone my body will calm down. Your articles give me hope and hope is everything when you feel so poorly all the time.
Dr. Izabella says
Jeannie – thank you so much for your support. I am so sorry you are not feeling well right now. Please understand I am not able to respond directly to these types of questions here. I highly recommend that you work with a functional medicine clinician. It’s an entire medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms.
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
CLINICIAN DATABASE
http://www.thyroidpharmacistconsulting.com/clinician-database.html
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://www.functionalmedicine.org/practitioner_search.aspx?id=117
Jamie Corley says
Hi Dr Wentz,
I have always wondered about what triggered my autoimmunity. Shortly before I started having trouble I got a severely painful case of strep throat and had to go to the ER. One strange thing was that I never got a fever. After that I developed Hashimotos and LPP a scarring auto immune hair loss. I am a 26 year old female and I am so sick of doctors not knowing what to do with me. Do you think strep could have played a part for me even though it’s not the infection associated with Hashimotos?
Dr. Izabella says
Jamie – thank you for reaching out. The most common triggers in Hashimoto’s are: nutrient deficiencies, food sensitivities, intestinal permeability (leaky gut), stress, an impaired ability to get rid of toxins and in some cases, infections. Optimizing your health starts with food. Figuring out which foods nourish you, and which ones cause you harm is the single most important thing you can learn in your health journey.
I’ve found that recognizing and eliminating reactive foods can be a life-changer for most people with Hashimoto’s.
Reactive foods trigger an inflammatory response in the GI tract, leading to malabsorption of nutrients (gluten sensitivity in particular has been implicated in causing a Selenium deficiency, a well known risk factor for Hashimoto’s), and can also produce intestinal permeability whenever they are eaten.
Most people will see a dramatic reduction in gut symptoms, brain symptoms, skin breakouts and pain by eliminating the foods that they are sensitive to. Some will also see a significant reduction in thyroid antibodies! An additional subset of people will actually be able to get their Hashimoto’s into complete remission just by getting off the foods they react to, normalizing their thyroid antibodies, and some even normalizing their thyroid function! Here are some articles which I wrote:
BEST DIET FOR HASHIMOTO’S AND HYPOTHYROIDISM
https://thyroidpharmacist.com/articles/best-diet-for-hashimotos-hypothyroidism
TAILORING YOUR THYROID DIET
https://thyroidpharmacist.com/articles/tailoring-your-thyroid-diet-to-your-needs
DAIRY AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/got-hashimotos-you-may-want-to-reconsider-dairy
CANDIDA AND HASHIMOTOS CONNECTION
https://thyroidpharmacist.com/articles/candida-and-hashimotos-connection/
Catherine Mangis says
Hi Dr. Wentz, ,
I was diagnosed with Hashimoto’s and hypothyroidism about a year and a half ago. After seeing my MD and Endocrinologist, both who told me there is nothing more to do but take Levothyroxine and test again in 12 weeks, I began seeing a Naturopath and reading through your Hashimoto’s Protocol book. Since it was only a short time since I began the Levothyroxine and I could barely function I quit taking it on my own. My Naturopath started me on several supplements like Selenium, B-Complex, Vitamin D, and Magnesium, which I am still taking. I also did a complete overhaul of our food and have been on a whole food diet since. We got water filters and I also changed out my beauty products and most household products. I feel better and so does my family, but I was still experiencing gut problems and fatigue. My Naturopath gave me several things to try at different times that did not help and in fact made it worse (Ashwaghanda, Thyrocsin, Biogest). The last, while taking the Biogest I started Nature-Throid. I noticed a lot of pain in what he called the RUQ and headaches. My labs came back decent, although my antibodies doubled. Since I had the same symptoms he increased it. He said since the fatigue hadn’t gotten significantly worse it was probably not EBV reactivated (I had it in college). With the increased dose, again, the same symptoms, but increased fatigue and confusion. I started to wonder if the pork had anything to do with it, because when I had it for breakfast I would get a headache. Well, my next labs went wonky. My TSH jumped to 22 while my T4 dropped to .64 and T3 was within range at 2.2. So he thought I just wasn’t tolerating the medicine and put me back on Levothyroxine. Much worse. I felt like I was back where I started a year ago. He said since I had such a reaction to it, I could stop it.
So now I am following your liver, adrenal, and gut guide-just started the gut protocol, laying off the pork and almonds (bloating, etc.) and if I don’t see improvement from there I guess I will need to request to be tested for an infection or something else. Is there anything else you can recommend to try or check that may explain the sudden change in my labs and where to go from here in regards to the fatigue and gut problems?
Dr. Izabella says
Catherine – thank you for sharing your thyroid healing journey here. We know that intestinal permeability (aka leaky gut) is present in every case of autoimmunity and often precedes the development of Hashimoto’s. Symptoms of leaky gut may include bloating, diarrhea, constipation, stomach aches, acid reflux and irritable bowel syndrome. According to the Institute of Functional Medicine, many people develop IBS 5-10 years before an autoimmune diagnosis. I was one of them and didn’t take my gut health as seriously as I should have. Gut problems are often caused by infections like H. pylori, parasites like Blasto, SIBO, an imbalance of bacteria, and enzyme deficiencies or food sensitivities (especially to gluten, dairy, and/or soy). Even stress can be a factor in gut permeability. Here is an article you might find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes/
Mary G says
Your article here on Infections seems to mostly relate to TPO. Would you say these three infections could also be the root cause of high thyroglobulin antibodies? I am asking because I was diagnosed with Hashimotos about a year and a half ago. So I changed my medication (to T4/T3) and my diet (no gluten, dairy, soy, and just a little sugar) which made my symptoms of low energy, brain fog, and hair loss go away. (yay!!) However, my thyroglobulin antibodies are going up again, after falling initially by a half. My TPO numbers are continuing to fall. So I thought I would test for an infection, but maybe that is not necessary if the infections are the root cause of high TPO and not high thyroglobulin antibodies. Any thoughts?
Dr. Izabella says
Mary We know that intestinal permeability (aka leaky gut) is present in every case of autoimmunity and often precedes the development of Hashimoto’s. Symptoms of leaky gut may include bloating, diarrhea, constipation, stomach aches, acid reflux and irritable bowel syndrome. According to the Institute of Functional Medicine, many people develop IBS 5-10 years before an autoimmune diagnosis. I was one of them and didn’t take my gut health as seriously as I should have. Gut problems are often caused by infections like H. pylori, parasites like Blasto, SIBO, an imbalance of bacteria, and enzyme deficiencies or food sensitivities (especially to gluten, dairy, and/or soy). Even stress can be a factor in gut permeability. Here is an article you might find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes/
Michelle Cullis says
I started following your 90 day protocol just under 3 weeks ago. Around ten days into the liver protocol I caught the flu and have been floored with it for ten days now. I would like your advice on how to proceed? I have been continuing with the liver protocol but Have had to take paracetamol for my symptoms and temperature.
Is this the right thing to do, should I take a break or move on to the adrenal protocol? I want to give this my best shot.
Dr. Izabella says
Michelle – thank you for following this page. For questions pertaining to the protocols please contact my team at info@thyroidpharmacist.com and they will be happy to help you.
AlliHi76 says
Can you have H. Pylori or another bacteria and not have stomach pain? I have Burning Mouth Syndrome and Hashimoto’s and I would love to figure out how to heal my mouth. I have cut out gluten, dairy, and a lot of sugar. I eat a lot more veggies than I used to, take Dr. Axe supplements for Leaky Gut and Thyroid function. And Vitamin D supplement (5000IU). I also use bone broth powder in smoothies and collagen powder. I am taking Armour Thyroid, but it is over-correcting my thyroid at this point, so my doctor said to not take it one day a week. I fainted recently, and think it has something to do with not taking it for a day, then taking it again. If you have any suggestions, I’m all ears:) Thank you!
Dr. Izabella says
Alli – Thank you for following this page. Please, understand that due to liability issues, I am unable to answer specific medical questions, but I highly recommend that you work with a functional medicine clinician. It’s an entire medical specialty dedicated to finding and treating underlying causes and prevention of serious chronic disease rather than disease symptoms. Here are some links which might help:
FUNCTIONAL MEDICINE APPROACH TO THE THYROID
https://thyroidpharmacist.com/articles/functional-medicine-approach-to-the-thyroid
CLINICIAN DATABASE
https://www.thyroidpharmacistconsulting.com/clinician-database.html
MY RECENT CHALLENGES AND FINDING DR. RIGHT
https://thyroidpharmacist.com/articles/my-challenges-and-finding-dr-right/
Sarah says
Dear Izabella,
Thank you for this blog and your work! It has been immensely helpful! Is there anyway you could give a brief condensed list of all GI pathogens we should ask to check at the doctors? I live abroad and can not request the lab test you recommended. Thank you, Sarah
Dr. Izabella says
Sarah – thank you for reaching out. We know that intestinal permeability (aka leaky gut) is present in every case of autoimmunity and often precedes the development of Hashimoto’s. Symptoms of leaky gut may include bloating, diarrhea, constipation, stomach aches, acid reflux and irritable bowel syndrome. According to the Institute of Functional Medicine, many people develop IBS 5-10 years before an autoimmune diagnosis. I was one of them and didn’t take my gut health as seriously as I should have. Gut problems are often caused by infections like H. pylori, parasites like Blasto, SIBO, an imbalance of bacteria, and enzyme deficiencies or food sensitivities (especially to gluten, dairy, and/or soy). Even stress can be a factor in gut permeability. Here is an article you might find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes/
Ilisa says
Hello, I did not take time to read comments, so my apologies if someone mentioned this. I am surprised you do not mention Matula Tea as a natural remedy for hPylori. I am taking that, for other reasons, but hPylori is it’s main focus in research and treatment, and with quite a bit of success from what I have read 🙂
Dr. Izabella says
Ilisa – thank you so much for sharing this! 🙂
Grace says
Hi Izabella,
Hi Izabella,
I have your root cause book and since then I have been trying to find my triggers. I tested negative for h pylori but when I saw two ladies that do kinesiology they said I had h pylori & that needed to be sorted first. I cut dairy out & 90% sugar (I have celiac so gluten free already for 6 years) and started taking a thyroid supplement & ginseng that the kinesiology ladies recommended. I started to have more energy initially & then I became hyper & feel terrible. I stopped taking everything supplements wise and had blood tests, my tsh was 0.08 and free t4 was 24.8. My dose for a long time has been 175mcg (I weight 5,8 at 56kgs, I believe that to be double the dose for my size) my antibodies are 360, they were 580 at diagnosis 7 years ago. I feel at a complete loss and don’t know what to do as my doctor doesn’t know anything about the condition, that’s the only other time my antibodies have been tested. I feel like I’m in a flare at the moment & have lots of infections going on. I don’t know what dose I should drop down too because taking any makes me feel worse. I forgot to take it for two days (was dropped down to 150mcg at this point) and it was the best I’d felt in longer then I could remember. I don’t know if I’m going into remission and it’s the medication making me feel awful or if I’m having a flare. I can’t find a functional doctor in my area. Any information or suggestions would be much appreciated.
Thank you
Dr. Izabella says
Grace – thank you so much for sharing your journey with me. I am so sorry your are struggling with this. I understand how hard this can be. <3 I believe that everyone needs to find a practitioner that will let him/her be a part of the healthcare team. You want someone that can guide you, that will also listen to you and your concerns. You want someone that’s open to thinking outside of the box and who understands that you may not fit in with the standard of care. It's a good idea to ask some standard questions when contacting a new doctor for the first time. Something else to consider is you can work with a functional doctor remotely, via Skype. You could also contact your local pharmacist or compounding pharmacy, who may be able to point you to a local doctor who has a natural functional approach. But I encourage you to keep looking for the right one for you! Here are some resources you might find helpful.
CLINICIAN DATABASE
https://www.thyroidpharmacistconsulting.com/pages/clinician-database
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://ifm.org/find-a-practitioner/
http://www.thyroidpharmacistconsulting.com/recommended-compounding-pharmacies.html
Mary Dunn says
I am starting to wonder if I need to be tested for gut infections. I have been on Hashimoto’s Protocol for 3 months and still feel chronically tired, plus am dealing with other issues. I am not on the right amount of thyroid. I take Armour Thyroid, but my test results showed that my free T3 are too low with Reverse T3 too high, so my Dr prescribed a T3 slow release compound, but whenever I try to take it, I go Hyperthyroid. She told me it’s because my adrenals need to heal, but after resting and doing the appropriate diet for this long, I would think they should be healed up.
I just got diagnosed with silent reflux (LPR) reflux which is a shock to me. I’ve only started having problems with swallowing for the past 6 months or so, but now my voice is hoarse and I cannot think why I would get it – I haven’t eaten gluten or dairy for about 8 years, but it almost seems worse since doing Hashimoto’s Protocol diet. So, it’s making me think that maybe an infection is behind it. There are no functional Dr’s close by where we live, so that isn’t an option right now. I’d love to hear your thoughts. Thank you.
Dr. Izabella says
Mary – thank you for reaching out and sharing your journey. I am so sorry to hear you are struggling. Hashimoto’s is a complicated condition with many layers that need to be unraveled. While conventional medicine only looks at each body system as a separate category and is only concerned with the thyroid’s ability to produce thyroid hormone, Hashimoto’s is more than just hypothyroidism. We know that intestinal permeability (aka leaky gut) is present in every case of autoimmunity and often precedes the development of Hashimoto’s. Symptoms of leaky gut may include bloating, diarrhea, constipation, stomach aches, acid reflux and irritable bowel syndrome. According to the Institute of Functional Medicine, many people develop IBS 5-10 years before an autoimmune diagnosis. I was one of them and didn’t take my gut health as seriously as I should have. Gut problems are often caused by infections like H. pylori, parasites like Blasto, SIBO, an imbalance of bacteria, and enzyme deficiencies or food sensitivities (especially to gluten, dairy, and/or soy). Even stress can be a factor in gut permeability. Here is an article you might find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes/
Tabitha says
I finally found an amazing doctor who advocates the theories in your book. That was one of my main pre-requisites. She is awesome, and everything I’ve been dealing with, she understands. She is a Hashimoto’s specialist in Altanta, and I drive about an hour and a half to her office. I know God led me to her! Her name is Dr. Bullington. I’ve been through MANY doctors. She finally did the right bloodwork, and we now know that I have one copy of the MTHFR gene mutation, I have systemic candida that she is treating with antifungals, liver support protocols, and is getting my thyroid medicine on the RIGHT track for the first time in a long time. She uncovered a UTI that I was trying to treat naturally. She put me on an antibiotic, which I am going to pick up today… I’m really praying this will not do more harm than good. I’ve literally not taken an antibiotic in more than 10 years. I try to do everything natural that I can. However, in this case, to rid my body of a UTI that’s been around too long, she is putting me on this. I’m so thankful for you advocating for us to find a GOOD doctor. This has been so amazing. I follow your general protocols for the most part, and I feel like God led me to you also. Since my Hashimoto’s diagnosis, this has been a journey to FIND the root cause, but I also know that each step is taking me one step closer to healing. I believe the underlying candida and the UTI may be what has been triggering my antibodies to go over 800. I’m excited to check them again in 4 months, on all these new natural supplements my doctor has me on, and see if they drop!! I can almost predict that they will be going DOWN for the first time in a long time. I can’t tell you how thankful I am for all of the labor that you put into sharing these life-changing recipes for those of us suffering from Hashimoto’s.
Dr. Izabella says
Tabitha – thank you so much for sharing your journey with me! <3 I am so happy to hear you have found a practitioner and i hope you will keep me posted on your progress. I would love it if you would share your doctor you have had great success with to our Recommended Practitioners database. It could make all the difference for someone who has been unable to find a good practitioner. Follow the link below and scroll to the bottom, then once you click "Accept" you'll then be able to see the lists and icons for each country: https://thyroidpharmacist.com/database-submit-your-thyroid-clinican-recommendation/
Sarah says
Hi Izabella,
I hope you are well! Thank you so much for your work! I am a long-term fan of yours and your book/articles have really helped me! Especially when doctors were dismissing me before I was finally diagnosed! I was wondering if it’s possible for Crypto to trigger Hashimotos/ Hypothyroidism?
Thank you!
Best wishes,
Sarah
Dr. Izabella says
Sarah – thank you so much for your support! You are so sweet! <3 We know that intestinal permeability (aka leaky gut) is present in every case of autoimmunity and often precedes the development of Hashimoto’s. Symptoms of leaky gut may include bloating, diarrhea, constipation, stomach aches, acid reflux and irritable bowel syndrome. According to the Institute of Functional Medicine, many people develop IBS 5-10 years before an autoimmune diagnosis. I was one of them and didn’t take my gut health as seriously as I should have. Gut problems are often caused by infections like H. pylori, parasites such as Blasto, SIBO, an imbalance of bacteria, and enzyme deficiencies or food sensitivities (especially to gluten, dairy, and/or soy). Even stress can be a factor in gut permeability. Here is an article you might find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes/
I recommend these tests: GI Maps Sample Report, Biohealth 401H Pathogens Report
The Biohealth 401H Pathogens tests for: Ova & Parasites x 4 (Trichrome stain) plus antigens to Giardia lamblia, Cryptosporidium parvum, and Helicobacter pylori. Plus culture x 1: Bacteria, fungi, yeasts, occult blood, Clostridium difficile: Colitis toxins A & B. The sample collection is over several days.
The GI Maps Test includes the first comprehensive pathogens assay that is FDA approved, the GPP assay by Luminex Corp. Pathogen targets include bacteria, parasites and another first for the market, viruses. The panel includes opportunistic organisms, normal flora, parasites, and fungi. DNA/PCR techniques also allow for the measurement of antibiotic resistance genes and virulence factors that contribute to pathogenicity. The GI Maps tests for the same as the 401H test, however, recently, the GI Maps has now added “worms” for testing as well. The sample collection is just one time.
Sachin Neupane says
I Have been living with chronic pharyngitis since the last 3 years. I was given antibiotics ,after 8-10Months I was diagnosed with hashimotos along with vitamin D insufficient. I cannot tolerate this every time I open my mouth in mirror I can see red spots on the neck wall.I am taking vitamin d tablets weekly.My anti tpo is also high 230.5 ..I don’t know what to do?Currently my tsh has come to normal,but I left taking medicines 4 months ago and in middle I went to aayurveda.And then I went to endocrinologist and he said he will check my TFT next month and start medicine if necessary..The ENT has given me medicines ,same medicines which I have been taking since beginning.I don’t know what is causing chronic pharyngitis.
Dr. Izabella Wentz says
Sachin – thank you for reaching out and sharing your journey. <3 I am so sorry to hear you are struggling with this. Hashimoto’s is often a combination of food sensitivities, nutrient deficiencies, adrenal issues, gut issues as well as an impaired ability to get rid of toxins. Any of those things would prevent a person from getting better. Hashimoto's is very much an individual condition. While there are root cause commonalities, each person will have their own or in some cases, more than one root cause. You will have to start with the simplest modifications, by removing triggers, followed by repairing the other broken systems to restore equilibrium, allowing the body to rebuild itself. You will need to dig down to why the immune system is imbalanced in the first place and this will tell you how you begin to finally feel better, reduce your thyroid antibodies and even take your condition into remission.
You will have to create your own health timeline. Look back at your overall history as far back as you can remember. Look for infections, periods of severe stress, the use of medications (especially antibiotics, antacids, and oral contraceptives), accidents, and exposure to toxins. These are events that may have contributed to Hashimoto's. Once you do, you will know what types of changes you need to implement to make yourself feel better.
If you need further support, please check out the list of lab tests inside the “Testing” chapter of my book, Hashimoto’s Root Cause. I also offer a 12-week program, Hashimoto's Self Management Program. Here are some resources I hope you find helpful as well.
BUILDING YOUR OWN HEALTH TIMELINE
https://thyroidpharmacist.com/sample-health-timeline/
Hashimoto’s Self-Management Program
https://thyroidpharmacist.com/enroll-in-hashimotos-self-management/
sheryl says
Hi,
A stool sample revealed that I have Cyclospora parasite and candida. I eat a very clean diet – all organic, no grains/ beans, plenty of good fat, veggies. I was told to take Bactrum (?) antibiotic for a week and another antibiotic for a whole month! I am very opposed to antibiotics and have not taken them since I was a child. Do you know of a specific herbal program that could possibly work to get rid of the parasite?
Dr. Izabella says
Sheryl – thank you for reaching out and sharing your journey. <3 We know that intestinal permeability (aka leaky gut) is present in every case of autoimmunity and often precedes the development of Hashimoto’s. Symptoms of leaky gut may include bloating, diarrhea, constipation, stomach aches, acid reflux and irritable bowel syndrome. According to the Institute of Functional Medicine, many people develop IBS 5-10 years before an autoimmune diagnosis. I was one of them and didn’t take my gut health as seriously as I should have. Gut problems are often caused by infections like H. pylori, parasites like Blasto, SIBO, an imbalance of bacteria, and enzyme deficiencies or food sensitivities (especially to gluten, dairy, and/or soy). Even stress can be a factor in gut permeability. Here is an article you might find interesting.
6 DIFFERENT ROOT CAUSES
https://thyroidpharmacist.com/articles/6-different-hashimotos-root-causes/
I talk more about parasites and candia in my book Hashimoto’s Protocol I hope you check it out. Here is a link:
http://amzn.to/2B5J1mq
Sara says
Great information and found the section on the types of infections particularly helpful. In my current state of hashimoto’s, I know something is “not working for me” when after I eat it, my hair falls out. If I eat something that I am responding to, my hair falls out the next morning. If I don’t eat any trigger foods, then my hair is just fine and I have more energy. The problem I have is that every time I try to supplement with any sort of vitamins (i.e. iron or b-vitamins or probiotics or vitamin D) my hair starts falling out. Any thoughts/recommendations/advice on why this might be occurring?
I tried searching myself for some answers and I came across a clinical study that said that Vitamin D is somehow connected to the EBV virus and that the body naturally down regulates its Vitamin D uptake on purpose to protect itself which is why some folks will have notoriously low vitamin D levels if EBV is present.
Dr. Izabella says
Sara – thank you so much for following this page and sharing your journey. <3 I am so sorry you are struggling with hair loss. Hair loss is a distressing symptom experienced by women with Hashimoto’s. For women, our hair represents our femininity, and losing our hair is a constant reminder that something is off and that we are not well.
Here are some articles which might help:
HAIR LOSS AND YOUR THYROID
https://thyroidpharmacist.com/articles/hair-loss-and-thyroid/
HASHIMOTO’S AND GETTING YOUR HAIR BACK
https://thyroidpharmacist.com/articles/hashimotos-and-getting-your-hair-back/
Epstein-Barr is a virus that causes mononucleosis (commonly called “Mono”), a debilitating viral infection that is common among college students and is also known as the “kissing disease,” because individuals are exposed to the virus through saliva of those who are infected. Specific immune cells known as CD8+ T cells are needed to fight off the Epstein-Barr virus, however, some individuals may have a low baseline level of these types of immune cells. (CD8+ T cells decrease with age, are lower in women, and in the presence of low vitamin D intake). When these fighter cells are low, the Epstein-Barr virus may take up residence in our organs (such as the thyroid) and essentially hijack the organ to help the virus hide and multiply. The timing of infection may also matter as well, for example, children in developing countries usually contract the Epstein-Barr Virus when they are under the age of 10. This usually results in an asymptomatic infection—one that does not cause symptoms. In contrast, in developed countries, where individuals are not usually exposed to the virus until they are in high school or college, the infection is symptomatic in 50% of the older kids affected. This is because by the time we reach college age, CD8+ T cells, the ones that fight EBV, have declined by threefold compared with the number of cells we had in childhood. You also need to be sure to ask for the Epstein Barr Virus Early Antigen test, as this is a test that will let us know if the virus is actively replicating. Here is a link which might help:
EPSTEIN-BARR VIRUS AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/epstein-barr-virus-and-hashimotos
Shannon Zerilli says
Hello
Could you help with Strep in bladder and female area. What are the treatments. Drs don’t believe me but I have tested positive for strep. They said strep is part of the normal flora. What can I take? I read celery juice? Thank you ? Shannon
Dr. Izabella says
Shannon – thank you for reaching out. I’m so sorry you are struggling with this. <3 I understand how frustrating and hard it is to find a practitioner that will listen. I believe that everyone needs to find a practitioner that will let him/her be a part of the healthcare team. You want someone that can guide you, that will also listen to you and your concerns. You want someone that’s open to thinking outside of the box and who understands that you may not fit in with the standard of care. It's a good idea to ask some standard questions when contacting a new doctor for the first time. Something else to consider is you can work with a functional doctor remotely, via Skype. You could also contact your local pharmacist or compounding pharmacy, who may be able to point you to a local doctor who has a natural functional approach. But I encourage you to keep looking for the right one for you! Here are some resources you might find helpful.
CLINICIAN DATABASE
https://thyroidpharmacist.com/database-recommended-clinicians/
FIND A FUNCTIONAL MEDICINE CLINICIAN
https://ifm.org/find-a-practitioner/
COMPOUNDING PHARMACIES
https://thyroidpharmacist.com/database-recommended-compounding-pharmacies/
Michelle K Towle says
Do you offer appointments?
I have always been hypo for many years. Since going thru menopause I have become hyper with Graves antibodies and also Hashi antibodies. My biggest issues have been the air hunger and now issues with my eyes. My thyroid labs have been coming down but the antibodies not so much. I am doing everything I can not to have my thyroid destroyed. I know that probiotics can help the antibodies. Which strains do you recommend for someone with hyper/Graves and also with Hashi antibodies? Any additional info would be greatly appreciated. Thanks.
Dr. Izabella Wentz says
Michelle – thank you for reaching out! ❤️ Swinging from hypo to hyper is common, people with Hashimoto’s can experience BOTH hypothyroid and hyperthyroid symptoms because as the thyroid cells are destroyed, stored hormones are released into the circulation causing a toxic level of thyroid hormone in the body, also known as thyrotoxicosis or Hashitoxicosis. Eventually, the stored thyroid may become depleted and due to thyroid cell damage, the person is no longer able to produce enough hormones. At this time, hypothyroidism develops. Air hunger is also common and is associated with Hashimoto’s. You’ll want to get your thyroid hormones checked and make sure your in the optimum ranges. As for consults, I do provide a limited number, however, at present time I am not accepting new clients. I have a 12 week online program called Hashimoto’s Self-Management Program, that covers all of the strategies that I go through with my one-on-one clients, in a self-paced format, so that participants have access to all of the things I’ve learned about Hashimoto’s without having to schedule costly consults with me or another practitioner. Here are some resources I hope you find helpful:
Hashimoto’s Self-Management Program
https://thyroidpharmacist.com/enroll-in-hashimotos-program/
THE MANY FACES OF HASHIMOTO’S
https://thyroidpharmacist.com/articles/the-many-faces-of-hashimotos/
10 FACTS ABOUT THYROID DISEASE
https://thyroidpharmacist.com/articles/need-know-thyroid-disease/
GRAVES AND HASHIMOTO’S
https://thyroidpharmacist.com/articles/graves-vs-hashimotos/
If you would like to be notified of any future consulting opportunities and educational events, you can sign up for my waiting list: https://thyroidpharmacist.com/dr-izabella-wentzs-waiting-list/