33: 11 Overlooked Strategies to Overcome Thyroid Fatigue

LISTEN TO THE PODCAST – Also available on Spotify and Apple Podcasts

Today on Thyroid Pharmacist Healing Conversations, we’re diving into a topic that so many of my clients and readers tell me is their number one struggle: fatigue.

I’m not just talking about the kind of tired that hits after a bad night’s sleep. I’m talking about soul-deep exhaustion — the kind where even after a full night in bed, you still feel like you’ve been hit by a truck. The kind that makes every task feel monumental, and every day feel like a marathon. I know that kind of fatigue all too well, because I lived it for years before I finally cracked the code.

In this episode, I’m walking you through the 11 most effective strategies I used to recover my energy, support my thyroid, and get back to feeling like myself. These are the exact tools I now share with clients, and I’ve seen them work time and time again. If you’re ready to trade exhaustion for vitality, this episode is for you.

What You’ll Learn in This Episode:

• Many people on thyroid medication still feel exhausted because their TSH isn’t truly optimized — most feel best with TSH between 0.5 and 2, ideally around 1.
• Fatigue can persist if you’re only taking T4 medications like Synthroid, without enough T3 support or proper T4 to T3 conversion — which requires nutrients like zinc, iron, and liver support.
• Low ferritin, B12, or folate can masquerade as thyroid fatigue, and many people need optimal — not just normal — levels to feel well (e.g., ferritin 90–110, B12 >700).
• A gluten-free diet often improves fatigue more than thyroid meds for some patients and may be crucial for those with food sensitivities like dairy, soy, corn, or eggs.
• Hidden blood sugar imbalances — like crashing after meals or feeling “hangry”— can drain energy, and stabilizing blood sugar with more protein, fat, and fiber can make a big difference.
• A simple dose of thiamine (B1) — 600 mg daily — has rapidly reversed fatigue in many cases, especially in people with low blood pressure, IBS, or long-standing exhaustion.
• Low stomach acid is common in hypothyroidism and contributes to post-meal fatigue; using Betaine with Pepsin or thiamine can dramatically improve digestion and energy.

Supplements We Discussed

• Rootcology Benfotamine – a bioavailable form of thiamine (vitamin B1) that can restore energy in as little as 3 days. (Use code PODCAST at checkout for a 20% discount.)
• Rootcology Carnitine Blend – includes both L-carnitine and acetyl-L-carnitine to support physical and mental energy. (Use code PODCAST at checkout for a 20% discount.)
• Betaine with Pepsin – aids protein digestion for those with low stomach acid.
• N-Acetyl-Cysteine (NAC) – supports liver detox and glutathione production.
• Vitamin D3 – essential for mood and energy; aim for levels between 60–80 ng/mL.
• B12, folate, and ferritin supplements – support oxygen delivery and cellular energy.

Other Tools and Resources

• Ulta Lab Tests Thyroid Panel – for uncovering hidden thyroid imbalances.
• My MedLab Alletess Food Panel 96 – checks for IgG reactions to 96 common foods.
• MyMedLab Alletess Food Panel 184 – checks for IgG reactions to 184 common foods.
• Blue Light Therapy Boxes – for vitamin D and seasonal mood support.
• Paleo Diet or Elimination Diet Templates – to identify food triggers.
• Listen to my conversation with Danielle Hamilton for more information on blood sugar balance.

Books and Articles About Thyroid Health

• 11 Strategies to Overcome Hashimoto’s Fatigue
• The Missing Link to Thyroid Fatigue
• How Does Carnitine Support Hashimoto’s?
• How Betaine with Pepsin Can Help with Hashimoto’s
• The 7 Most Common Nutrient Deficiencies in Hashimoto’s
• Top 10 Thyroid Tests and How to Interpret Them
• A Pharmacist’s Review of Medications for Hashimoto’s and Hyperthyroidism
• How Supporting the Liver is Key to Recovering from Thyroid Disease
• Are Your Adrenals Sabotaging Your Health
• Why Addressing Adrenals is a Must if You Have a Thyroid Problem
• Self-Care Resources for Adrenal Healing

Learn More About My Fatigue and Brain Fog Program

Get the Full Episode Transcript

Let’s Connect!

• Follow me on Instagram:@izabellawentzpharmd
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• Subscribe & Review: If you loved this episode, please leave a review on Apple Podcasts or Spotify!

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Got questions? Drop them in the comments! 🙂

About Our Host

Dr. Izabella Wentz 

Dr. Izabella Wentz is a compassionate, innovative, solution-focused integrative pharmacist dedicated to finding the root causes of chronic health conditions. Her passion stems from her own diagnosis of Hashimoto’s thyroiditis in 2009, following a decade of debilitating symptoms.

Dr. Izabella Wentz has written several best-selling books, including the New York Times bestseller Hashimoto’s Thyroiditis: Lifestyle Interventions for Finding and Treating the Root Cause, the protocol-based #1 New York Times bestseller Hashimoto’s Protocol: A 90-Day Plan for Reversing Thyroid Symptoms and Getting Your Life Back, the Wall Street Journal bestseller Hashimoto’s Food Pharmacology: Nutrition Protocols and Healing Recipes to Take Charge of Your Thyroid Health, and her latest book, Adrenal Transformation Protocol.

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