Dr. Izabella Wentz, PharmD

Thyroid Pharmacist

Podcast Episode 28: Rewire Your Brain to Heal: Biohacking the Mental Patterns That Keep Us Sick

28: Rewire Your Brain to Heal: Biohacking the Mental Patterns That Keep Us Sick

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LISTEN TO THE PODCAST – Also available on Spotify and Apple Podcasts

In this episode of the Thyroid Pharmacist Healing Conversations podcast, I interviewed one of my favorite people, Dave Asprey, aka “The Father of Biohacking.” Dave is also the founder of Bulletproof Coffee and Danger Coffee, and the author of several bestselling books.

People often ask me how I am able to stay so calm and resilient and grounded, despite all of the challenges I have gone through… earlier in life, and even recently. My secret? I happen to be good friends with the “Father of Biohacking,” Dave Asprey. Back in 2014, I had healed my physical body, but let’s just say that my brain still needed some work. I was easily triggered, overwhelmed, and walking around with a lot of unresolved trauma, which made me push my body to the limits. It’s a bit of a vicious cycle I see with autoimmune clients – they tend to heal their physical bodies, but then they jump into the same patterns that get them sick again (overworking, not listening to their bodies, overcommitting, etc.). I met Dave at a wellness conference in January 2014, and was surprised that he knew who I was and had even read my book, Hashimoto’s The Root Cause. It turns out, he also has Hashimoto’s, and was able to get it into remission! We became fast friends. 🙂

Dave introduced me to neurofeedback, a $10,000+ therapy that completely rewired my mind and stress response. I know this therapy is not accessible to everyone, and I am so grateful to have had Dave on my podcast, Thyroid Pharmacist Healing Conversations, on how to biohack rewiring your brain. Because sometimes your brain and mindset can be what prevents you from healing, and you can also heal your physical body, but your brain and mindset can make you get sick over again due to the same patterns. Dave shares a multitude of methods on how to rewire your brain for healing, including ones that are free and can be done in your own home. Hint: meditation is one way, but it’s not the only way (and often not the best way out).

Dave also discusses these tools in his latest book, Heavily Meditated: 8 Steps to Remove Your Triggers and Upgrade Your Focus, Energy, and Inner Peace. The book uses ancient wisdom, modern technology, and science to show readers how to improve cognitive function, reduce stress, improve emotional resilience, enjoy greater creativity, and even nurture their relationships through effective meditation. He is also hosting an upcoming Biohacking Conference, Live Beyond 180 – register here!

Dave’s journey through health challenges, including Hashimoto’s and chronic fatigue, has fueled his passion for helping others break free from negative mental patterns. He is living proof that your mindset could be keeping you from healing – but does not need to keep you stuck.

If you’re ready to explore how you can work smarter, not harder, to reclaim your health, and how to rewire your brain to live your best life, this episode is a must-listen!

What you’ll learn in this episode:

  • Meditation helps rewire the brain out of chronic stress, can reduce inflammation and improve neuroplasticity. These changes are especially relevant for people with autoimmune conditions, PTSD, or brain fog, as they promote healing and cognitive flexibility, as well as improve emotional regulation, focus, and resilience.
  • Not every brain is wired for traditional meditation. Fast-thinking, high-reactive brains (sometimes called “hunter brains”) may find sitting meditation frustrating or even dysregulating. These individuals often do better with active or tech-assisted practices.
  • Neurofeedback is one powerful alternative to traditional meditation. It uses real-time brainwave feedback to train the brain into calm, focused states — without requiring years of practice. Results can include better sleep, less reactivity, and enhanced cognitive clarity. But there are also many others. 🙂
  • Healing the body doesn’t automatically rewire the stress response. Izabella shared how even after remission from Hashimoto’s, her brain patterns remained stuck in fear and overwork — until she incorporated adrenal and brain retraining tools like neurofeedback and adaptogens.
  • Trigger management is energy management. Every unresolved trigger drains energy — and adrenal recovery (both physiologic and emotional) frees up that energy for healing, joy, and growth.

Guest Resources/Connect with Dave Asprey

Supplements We Discussed

  • Vitamin DAKE A blend of essential fat-soluble vitamins that support hormone balance and immune function.
  • Tyrosine and Rhodiola – Cognitive enhancers that help improve stress resilience and mental clarity. Contained in many adrenal support products including Rootcology Adrenal Support
  • Carnitine: Highlighted as beneficial for brain health and energy.
  • Benfotiamine (Fat-soluble Vitamin B1): Highlighted by Izabella as her top cognitive supplement for supporting blood pressure and energy levels.
  • Minerals 101: A foundational mineral supplement by Dave to replenish trace minerals needed for mitochondrial function.
  • Protein + Betaine HCL + Enzymes: Used to improve digestion and absorb high levels of protein for muscle building and mitochondrial repair.

Other Tools and Resources

  • TrueDark Glasses: Circadian rhythm-supportive eyewear created by Dave to block junk light and promote better sleep and hormone balance.
  • Neurofeedback: A technique that rewires the brain to improve mental function.
  • Red Light Therapy is a wellness tool that uses specific light wavelengths to stimulate cellular function and healing.
  • Cryotherapy is a cold exposure treatment used to reduce inflammation and promote metabolic resilience.
  • 40 Years of Zen (Neurofeedback Facility): Dave’s intensive neurofeedback program that helps rewire the brain, dissolve emotional triggers, and increase self-awareness in a compressed timeline.
  • Reset Process (Technique featured in Heavily Meditated): An 8-step method to permanently deactivate emotional triggers and reprogram the nervous system.
  • Muse Headband: A neurofeedback meditation device that measures brain activity to encourage focused meditation, though noted as ineffective for some high-performing brains.
  • EMDR, or Eye Movement Desensitization and Reprocessing, is a method used by psychotherapists to help people eliminate the lasting effects of traumatic events.
  • French White Flour + Sourdough: Dave’s workaround for gluten sensitivity—fermented organic flour from France, which he tolerates without symptoms.
  • Cold Exposure / Cold Showers / Salad Bowl Plunge: Used for dopamine reset and nervous system regulation via brief intentional discomfort.
  • Somatic Therapy + Conscious Restraint: Referenced via Kimmy Inch, using physical constraint to safely induce parasympathetic states.
  • Tantric Practices: Discussed as alternate pathways to healing and accessing altered states of awareness.
  • BICEP (Brief, Intentional, Conscious Exposure to Pain): A technique to reset dopamine sensitivity and build emotional resilience.

More Books and Articles

Get the Full Episode Transcript

Let’s Connect!

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Got questions? Drop them in the comments! 🙂

About Our Host

Dr. Izabella Wentz 

Dr. Izabella Wentz is a compassionate, innovative, solution-focused integrative pharmacist dedicated to finding the root causes of chronic health conditions. Her passion stems from her own diagnosis of Hashimoto’s thyroiditis in 2009, following a decade of debilitating symptoms.

Dr. Izabella Wentz has written several best-selling books, including the New York Times bestseller Hashimoto’s Thyroiditis: Lifestyle Interventions for Finding and Treating the Root Cause, the protocol-based #1 New York Times bestseller Hashimoto’s Protocol: A 90-Day Plan for Reversing Thyroid Symptoms and Getting Your Life Back, the Wall Street Journal bestseller Hashimoto’s Food Pharmacology: Nutrition Protocols and Healing Recipes to Take Charge of Your Thyroid Health, and her latest book, Adrenal Transformation Protocol.

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About Our Guest

Dave Asprey is the founder of Bulletproof Coffee, the Bulletproof Diet, and the biohacking movement. Known as the “Father of Biohacking,” he is a 4x New York Times bestselling author and host of The Human Upgrade podcast. His latest book, Heavily Meditated (Harper Collins, May 2025), offers a fast path to dissolving stress and achieving inner peace. Dave is also the founder of Upgrade Labs, creator of the Biohacking Conference, and CEO of Danger Coffee. He’s helped millions upgrade their bodies and minds for peak performance and longevity. Heavily Meditated: The Fast Path to Remove Your Triggers, Dissolve Stress, and Activate Inner Peace launches May 20, 2025 (Harper Collins).

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