Dr. Izabella Wentz, PharmD

Thyroid Pharmacist

32: Hangry & Hormonal? Metabolic Hypoglycemia, Weight Loss Resistance & Your Thyroid | Danielle Hamilton

32: Hangry & Hormonal? Metabolic Hypoglycemia, Weight Loss Resistance & Your Thyroid | Danielle Hamilton

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Did you know that while the world out there is focused on high blood sugar, many people with hypothyroidism may actually have low blood sugar (hypoglycemia)? For some, this may be more damaging than high blood sugar!

I’m excited to share this episode of the Thyroid Pharmacist Healing Conversations podcast, where I interviewed Danielle “Dani” Hamilton, a functional nutritional therapy practitioner and renowned blood sugar expert. Dani specializes in using a personalized circadian and quantum approach to optimize metabolic health. Her journey into this field was fueled by her own struggles with PCOS, hypoglycemia, acne, and weight loss resistance. Through her determination, she successfully reversed these issues after discovering that blood sugar and metabolic health were at the root of her challenges.

Throughout her career, Dani has helped hundreds reverse metabolic issues like insulin resistance. However, she noticed that some individuals continued to struggle despite doing “everything right.” This prompted her to dig deeper, turning to nature for answers and uncovering the incredible power of light, water, and magnetism in optimizing not just metabolic health, but every aspect of well-being.

What you’ll learn in this episode:

  • Why low blood sugar might be sabotaging your thyroid health: Hypoglycemia often flies under the radar in hypothyroidism and may be responsible for increased thyroid antibodies, fatigue, an inability to lose weight, anxiety, insomnia, cravings, and mood swings.
  • Metabolic hypoglycemia is under-recognized: Many people experience symptoms like shakiness, anxiety, brain fog, or waking at 2 am, even with blood sugar levels in the 70s or 80s — levels that are often dismissed by doctors as “normal.”
  • Hypoglycemia can drive hormonal chaos: Dani reversed her PCOS not by directly treating hormones but by stabilizing her blood sugar. Dysregulated blood sugar disrupts thyroid function, sex hormones, cortisol, and even fertility.
  • Your “personality traits” may be symptoms: Cravings, being “hangry,” needing snacks constantly, or being unable to skip meals are not just quirks — they’re often signs of blood sugar instability and metabolic dysfunction.
  • Sunlight, not just food, fuels metabolism: Infrared and UVA light from the sun play a crucial role in mitochondrial health, blood sugar regulation, fat burning, and thyroid hormone activation. Dani emphasized our modern “sunlight deficiency” as a key factor in fatigue and metabolic issues.
  • Leptin tells your body whether it’s safe to burn fat: Low leptin, common in over-stressed, underfed, overexercised women, suppresses thyroid function and keeps the body in famine mode. The solution isn’t more fasting — it’s strategic nourishment and nervous system regulation.

Guest Resources/Connect with Danielle Hamilton

Supplements We Discussed

  • Carnitine – Supports fat metabolism and can help with hypoglycemia.
  • Chromium – May assist in regulating blood sugar levels.
  • Metformin – Diabetes medication referenced for PCOS and insulin resistance. (Read more about it in my article here.)
  • N-acetyl cysteine (NAC) – Discussed as a potential supplement for metabolic health.
  • Thiamine (Vitamin B1) – Essential for metabolism and energy production.
  • Magnesium – Note: Magnesium can drop blood sugar too much in some sensitive individuals.
  • Sodium, Potassium, and Electrolytes – Essential for energy stability and metabolic function.
  • Vitamin D – Critical for immune and thyroid health; best sourced from the sun.
  • Pregnenolone & DHEA – Can be used to support the adrenals.
  • Fulvic and Humic Minerals – Recommended for overall mineral support and detoxification.
  • Spironolactone – Used for hormonal acne and PCOS.
  • Vanadium – A micronutrient that may be deficient in those with blood sugar issues and diabetes.
  • Myo-Inositol and D-Chiro-Inositol – Recommended for sleep, blood sugar issues , and PCOS.
  • Omega-3s – Needed for proper fat metabolism.
  • Digestive Support – Stomach acid, pancreatic enzymes, and bile support critical for nutrient absorption and fat digestion.

Other Tools and Resources

  • Continuous Glucose Monitor – Used to detect hypoglycemia and glucose trends in real time.
  • Organic Acids Test (OAT) by Mosaic Diagnostics – Used to uncover metabolic imbalances including in children.
  • Stomach Acid and Digestive Enzymes – Important for nutrient absorption and metabolic health.
  • Red light therapy – For mitochondrial and glucose support, especially in winter. (Use discount code Thyroid10 for 10% off Orion red light therapy products.)
  • Morning sunlight exposure – A key circadian rhythm reset to support adrenal and blood sugar health.
  • Grounding (earthing) – Barefoot connection to the earth’s surface helps recharge your body, support mitochondrial function, and enhance metabolic health.
  • Cold exposure (walks, wrist/face dunks) – Helps improve mitochondrial health and supports blood sugar regulation.
  • Brown adipose tissue (BAT) – Activated by cold and sunlight to support metabolism.
  • Meal timing based on sun exposure – Eating during daylight to enhance glucose metabolism.
  • Forest bathing – A powerful practice for calming the nervous system and nourishing your adrenals. Reconnecting with nature can lower stress hormones and restore balance.
  • Coffee enemas – Mentioned in Danielle’s personal healing journey.
  • Sprouts Market – Where Danielle buys her favorite healing fish: black cod (sablefish).
  • Breathable routines (like circadian-aligned eating/sleeping) – Suggested for low leptin and hypoglycemia recovery.
  • Vitamin D from sun exposure – Emphasized over synthetic supplementation for its biological complexity.
  • Melatonin (endogenous, light-driven) – Described as a mitochondrial antioxidant activated by infrared light.

Key Dietary & Metabolic Protocols

  • Keto as a temporary tool – Used therapeutically, but not recommended long-term for most.
  • Carb “staircase” approach – Gradual carb reductions to avoid hypoglycemia.
  • Sunlight as a nutrient – UVA and infrared light vital for health.
  • Melanin & “solar callus” – Adaptation through safe sun exposure.

Books and Articles About Thyroid Health and Blood Sugar

This episode is a must-listen for anyone struggling with blood sugar issues, especially those with thyroid conditions. Tune in to gain valuable insights and actionable tips to take control of your metabolic health!

Get the Full Episode Transcript

Let’s Connect!

If this podcast resonates with you, don’t forget to share with a friend who needs this information!

Got questions? Drop them in the comments! 🙂

About Our Host

Dr. Izabella Wentz 

Dr. Izabella Wentz is a compassionate, innovative, solution-focused integrative pharmacist dedicated to finding the root causes of chronic health conditions. Her passion stems from her own diagnosis of Hashimoto’s thyroiditis in 2009, following a decade of debilitating symptoms.

Dr. Izabella Wentz has written several best-selling books, including the New York Times bestseller Hashimoto’s Thyroiditis: Lifestyle Interventions for Finding and Treating the Root Cause, the protocol-based #1 New York Times bestseller Hashimoto’s Protocol: A 90-Day Plan for Reversing Thyroid Symptoms and Getting Your Life Back, the Wall Street Journal bestseller Hashimoto’s Food Pharmacology: Nutrition Protocols and Healing Recipes to Take Charge of Your Thyroid Health, and her latest book, Adrenal Transformation Protocol.

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About Our Guest

Danielle “Dani” Hamilton is a Functional Nutritional Therapy Practitioner and a renowned blood sugar expert specializing in using a personalized circadian and quantum approach to optimizing metabolic health. Her journey into this specialized field was fueled by her personal battle with PCOS, hypoglycemia, acne, and weight loss resistance, which she successfully reversed after learning that blood sugar issues and metabolic issues were at the root.

After working with clients for several years and helping hundreds reverse their metabolic issues like insulin resistance, there were others who continued to struggle, despite doing “everything right.” Encouraged to dig deeper, Dani turned to nature for answers and discovered the incredible power of light, water and magnetism to help optimize not only metabolic health, but every single aspect of health. Lit up by the sun’s healing powers, she now uses a circadian and quantum approach as a foundation for helping her clients heal.

Dani is on a mission to help the world get back to nature to heal their blood sugar, uplevel their energy, and feel great. She is the host of the top 50 Nutrition Podcast, Light Up Your Metabolism. She is also the creator of the transformative “Blood Sugar Mastery Program.”

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