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Many of my clients come to me with thyroid issues and Hashimoto’s, and tell me that they just can’t seem to lose weight, no matter what they try. Despite what the “gym bros” would like us to believe, we now know that there’s a lot more to weight loss than calories in/calories out. So if you’re struggling with this too, please know that there’s nothing wrong, and there are likely some “hidden” factors that conventional doctors aren’t always addressing.
I’m so excited to introduce my guest, McCall McPherson, a pioneering physician associate and entrepreneur in thyroid, hormone, and metabolic health. Her focus on personalized, innovative solutions to weight loss (especially for women with thyroid conditions), is based on her medical expertise and personal experience. And, like myself, she advocates for a balanced, tailored approach to helping people reach their wellness goals.
In this episode, we take a deep dive into some of the strategies we can use today to address weight loss with thyroid and metabolic issues, including:
- Many thyroid patients remain symptomatic on T4-only medications like levothyroxine due to poor conversion to active T3 — caused by stress, nutrient deficiencies, or genetics.
- Subclinical hypothyroidism is often just early-stage hypothyroidism — waiting to treat it delays healing and impacts quality of life.
- T3-containing medications like Cytomel or Natural Desiccated Thyroid (NDT) can dramatically improve symptoms like fatigue, hair loss, and depression.
- GLP-1 medications (like semaglutide), when microdosed and paired with lifestyle support, help thyroid patients lose weight and heal underlying metabolic dysfunction.
- These medications may also reduce inflammation and Hashimoto’s antibodies when used appropriately.
- Studies do not show increased thyroid cancer risk from GLP-1s in humans; concerns stem from outdated rat studies using mega-doses.
- Success with GLP-1s depends on personalized, low dosing, strength training, proper nutrition, and lab monitoring — not just taking a shot and hoping for the best.
If you’ve been struggling to lose weight and would like to learn more about the pros and cons of weight loss medications, give this episode a listen.
Free Resource from Our Guest
Supplement We Discussed
Other Tools and Resources
- Low Dose Naltrexone and Hashimoto’s
- Glucagon-Like Peptide 1 Receptor Agonists and Risk of Thyroid Cancer: An International Multisite Cohort Study
- Thyroid Testing – Full Thyroid Panel test with Ulta Labs
Books and Articles
- Top 10 Thyroid Tests and How to Interpret Them
- Finding Your Root Cause: Key Lab Tests
- How to Lose Weight With Hashimoto’s
- A Pharmacist’s Review of Medications for Hashimoto’s and Hypothyroidism
- How to Shrink Thyroid Nodules
- Blood Sugar Balance and Thyroid Health
Get the Full Episode Transcript
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Got questions? Drop them in the comments! 🙂
About Our Host
Dr. Izabella Wentz
Dr. Izabella Wentz is a compassionate, innovative, solution-focused integrative pharmacist dedicated to finding the root causes of chronic health conditions. Her passion stems from her own diagnosis of Hashimoto’s thyroiditis in 2009, following a decade of debilitating symptoms.
Dr. Izabella Wentz has written several best-selling books, including the New York Times bestseller Hashimoto’s Thyroiditis: Lifestyle Interventions for Finding and Treating the Root Cause, the protocol-based #1 New York Times bestseller Hashimoto’s Protocol: A 90-Day Plan for Reversing Thyroid Symptoms and Getting Your Life Back, the Wall Street Journal bestseller Hashimoto’s Food Pharmacology: Nutrition Protocols and Healing Recipes to Take Charge of Your Thyroid Health, and her latest book, Adrenal Transformation Protocol.
Thyroid Pharmacist Blog
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About Our Guest
McCall McPherson is a pioneering physician associate and entrepreneur in thyroid, hormone, and metabolic health. As founder of Modern Thyroid Clinic, co-owner of Modern Weight Loss, and owner of Thyroid Nation, she combines medical expertise with personal experience to offer innovative solutions as well as a unique and balanced approach to wellness. A TEDx speaker, honored in the top 200 Fastest Growing Health Companies on 2024’s Inc 5000 list, and the host of the podcast Modern Thyroid & Wellness, McCall’s unique approach stems from her journey as both practitioner and patient.
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